皮质骨的屈服后及失效特性。
Post-yield and failure properties of cortical bone.
作者信息
Wolfram Uwe, Schwiedrzik Jakob
机构信息
School of Engineering and Physical Science, Institute for Mechanical, Process and Energy Engineering, Heriot-Watt University , Edinburgh, UK.
Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Mechanics of Materials and Nanostructures , Thun, Switzerland.
出版信息
Bonekey Rep. 2016 Aug 24;5:829. doi: 10.1038/bonekey.2016.60. eCollection 2016.
Abstract
Ageing and associated skeletal diseases pose a significant challenge for health care systems worldwide. Age-related fractures have a serious impact on personal, social and economic wellbeing. A significant proportion of physiological loading is carried by the cortical shell. Its role in the fracture resistance and strength of whole bones in the ageing skeleton is of utmost importance. Even though a large body of knowledge has been accumulated on this topic on the macroscale, the underlying micromechanical material behaviour and the scale transition of bone's mechanical properties are yet to be uncovered. Therefore, this review aims at providing an overview of the state-of-the-art of the post-yield and failure properties of cortical bone at the extracellular matrix and the tissue level.
摘要
衰老及相关骨骼疾病给全球医疗保健系统带来了重大挑战。与年龄相关的骨折对个人、社会和经济福祉都有严重影响。相当一部分生理负荷由皮质骨承担。其在衰老骨骼中对整个骨骼抗骨折能力和强度的作用至关重要。尽管在宏观层面已积累了大量关于该主题的知识，但潜在的微观力学材料行为以及骨力学性能的尺度转变仍有待揭示。因此，本综述旨在概述细胞外基质和组织水平上皮质骨屈服后及失效特性的最新研究状况。
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