Gaur Sumit, Agnihotri Rupali
Department of Pedodontics and Preventive Dentistry, Manipal College of Dental Sciences, Manipal University, Manipal, Karnataka, 576104, India.
Department of Periodontology, Manipal College of Dental Sciences, Manipal University, Manipal, Karnataka, 576104, India.
Biol Trace Elem Res. 2017 Apr;176(2):225-238. doi: 10.1007/s12011-016-0832-y. Epub 2016 Aug 31.
Trace mineral micronutrients are imperative for optimum host response. Populations worldwide are prone to their insufficiency owing to lifestyle changes or poor nutritional intake. Balanced levels of trace minerals like iron (Fe), zinc (Zn), selenium (Se) and copper (Cu) are essential to prevent progression of chronic conditions like periodontitis. Their excess as well as deficiency is detrimental to periodontal health. This is specifically true in relation to Fe. Furthermore, some trace elements, e.g. Se, Zn and Cu are integral components of antioxidant enzymes and prevent reactive oxygen species induced destruction of tissues. Their deficiency can worsen periodontitis associated with systemic conditions like diabetes mellitus. With this background, the present review first focusses on the role of four trace minerals, namely, Fe, Zn, Se and Cu in periodontal health followed by an appraisal of the data from case control studies related to their association with chronic periodontitis.
微量矿物质微量元素对于宿主的最佳反应至关重要。由于生活方式的改变或营养摄入不足,全球人群都容易出现这些元素的缺乏。铁(Fe)、锌(Zn)、硒(Se)和铜(Cu)等微量矿物质的平衡水平对于预防牙周炎等慢性疾病的进展至关重要。它们的过量和缺乏都会对牙周健康有害。铁尤其如此。此外,一些微量元素,如硒、锌和铜是抗氧化酶的组成成分,可防止活性氧诱导的组织破坏。它们的缺乏会使与糖尿病等全身性疾病相关的牙周炎恶化。在此背景下,本综述首先关注四种微量矿物质,即铁、锌、硒和铜在牙周健康中的作用,然后评估病例对照研究中关于它们与慢性牙周炎关联的数据。