Mbarki Houda, Belghiti Khadija Alaoui, Harmouch Taoufiq, Najdi Adil, Arrayhani Mohamed, Sqalli Tarik
Service de Néphrologie, CHU Hassan II, Fès, Maroc.
Laboratoire d'Anatomopathologie, CHU Hassan II, Fès, Maroc; Faculté de Médecine et de Pharmacie de Fès, Maroc.
Pan Afr Med J. 2016 May 6;24:21. doi: 10.11604/pamj.2016.24.21.3982. eCollection 2016.
The contribution of renal needle biopsy (RNB) to make a diagnosis, a treatment selection and a prognostic evaluation of nephropathies is significant. No Moroccan study has evaluated the practice and the contribution of RNB. Our aim was to study RNB indications, to determine the frequency of kidney diseases identified by RNB in our region and make a comparison between clinical and biological data and histological diagnosis. This is a retrospective study conducted between January 2009 and December 2012. We included all patients in the Department of Nephrology, CHU Hassan II, Fez, who underwent biopsy of native kidneys. 522 RNB were performed. We excluded 8 biopsies due to lack of informations and 514 were retained. The average age of the patients at the time of RNB was 39±17 years (3-82 years). Sex ratio was 0.9. Nephrotic syndrome was the most common clinical diagnosis to all ages (58.2%). Glomerular nephropathies represent 94,2% of diagnosed renal diseases, their distribution varies according to patients' age. RNB confirmed the first clinically suspected diagnosis in 40.65% of cases, whereas it revealed an unexpected diagnosis in 22.5% of them. Syndromic diagnosis can orient the clinician toward the most probable kidney disease and guide any emergency treatment while awaiting RNB results. But it can never replace RNB which remains the gold standard.
肾穿刺活检（RNB）在肾病的诊断、治疗选择及预后评估方面具有重要作用。尚无摩洛哥的研究对RNB的应用情况及其作用进行评估。我们的目的是研究RNB的适应证，确定我们地区通过RNB确诊的肾脏疾病的发生率，并比较临床和生物学数据与组织学诊断结果。这是一项于2009年1月至2012年12月期间开展的回顾性研究。我们纳入了拉巴特哈桑二世大学医院肾脏病科所有接受过自体肾活检的患者。共进行了522例RNB。因信息缺失排除了8例活检，保留了514例。RNB时患者的平均年龄为39±17岁（3至82岁）。性别比为0.9。肾病综合征是各年龄段最常见的临床诊断（58.2%）。肾小球疾病占确诊肾脏疾病的94.2%，其分布因患者年龄而异。RNB在40.65%的病例中证实了最初临床怀疑的诊断，而在22.5%的病例中揭示了意外诊断。综合征诊断可使临床医生倾向于最可能的肾脏疾病，并在等待RNB结果期间指导任何紧急治疗。但它永远无法取代RNB，RNB仍是金标准。
