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Bone Marrow Takes Center Stage in Cardiovascular Disease.

作者信息

Swirski Filip K, Nahrendorf Matthias

机构信息

From the Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston.

出版信息

Circ Res. 2016 Sep 2;119(6):701-3. doi: 10.1161/CIRCRESAHA.116.309584.

DOI:10.1161/CIRCRESAHA.116.309584
PMID:27587406
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5012290/
Abstract
摘要

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本文引用的文献

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CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis.抗CD47抗体可恢复吞噬作用并预防动脉粥样硬化。
Nature. 2016 Aug 4;536(7614):86-90. doi: 10.1038/nature18935. Epub 2016 Jul 20.
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LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis.LNK/SH2B3功能丧失促进动脉粥样硬化和血栓形成。
Circ Res. 2016 Sep 2;119(6):e91-e103. doi: 10.1161/CIRCRESAHA.116.308955. Epub 2016 Jul 18.
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The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease.全基因组关联研究对心血管疾病病理生理学及治疗的影响。
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KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.KLF4 依赖的平滑肌细胞表型调节在动脉粥样硬化斑块发病机制中起关键作用。
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Lifestyle effects on hematopoiesis and atherosclerosis.生活方式对造血和动脉粥样硬化的影响。
Circ Res. 2015 Feb 27;116(5):884-94. doi: 10.1161/CIRCRESAHA.116.303550.
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Interleukin-3/granulocyte macrophage colony-stimulating factor receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with hematopoietic ApoE deficiency.白细胞介素-3/粒细胞巨噬细胞集落刺激因子受体促进造血 ApoE 缺陷小鼠的干细胞扩增、单核细胞增多和动脉粥样硬化巨噬细胞负荷。
Arterioscler Thromb Vasc Biol. 2014 May;34(5):976-84. doi: 10.1161/ATVBAHA.113.303097. Epub 2014 Mar 20.
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Local proliferation dominates lesional macrophage accumulation in atherosclerosis.局部增殖主导动脉粥样硬化病灶中巨噬细胞的积累。
Nat Med. 2013 Sep;19(9):1166-72. doi: 10.1038/nm.3258. Epub 2013 Aug 11.
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Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure.白细胞在动脉粥样硬化、心肌梗死和心力衰竭中的作用。
Science. 2013 Jan 11;339(6116):161-6. doi: 10.1126/science.1230719.
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Genetics of human cardiovascular disease.人类心血管疾病的遗传学。
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Elevated CD14++CD16- monocytes predict cardiovascular events.CD14++CD16-单核细胞水平升高预示心血管事件。
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