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禽源大肠杆菌菌株IHIT25637的基因组序列，该菌株是ST131型肠外致病性大肠杆菌，携带编码黏菌素耐药决定子MCR-1。

Genome Sequence of Avian Escherichia coli Strain IHIT25637, an Extraintestinal Pathogenic E. coli Strain of ST131 Encoding Colistin Resistance Determinant MCR-1.

作者信息

Ewers Christa, Göttig Stephan, Bülte Maria, Fiedler Sophie, Tietgen Manuela, Leidner Ursula, Heydel Carsten, Bauerfeind Rolf, Semmler Torsten

机构信息

Institute of Hygiene and Infectious Diseases of Animals, Justus Liebig University, Giessen, Germany

Institute of Medical Microbiology and Infection Control, Hospital of the Johann Wolfgang von Goethe-University, Frankfurt am Main, Germany.

出版信息

Genome Announc. 2016 Sep 1;4(5):e00863-16. doi: 10.1128/genomeA.00863-16.

DOI:10.1128/genomeA.00863-16
PMID:27587807
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5009964/
Abstract

Sequence type 131 (ST131) is one of the predominant Escherichia coli lineages among extraintestinal pathogenic E. coli (ExPEC) that causes a variety of diseases in humans and animals and frequently shows multidrug resistance. Here, we report the first genome sequence of an ST131-ExPEC strain from poultry carrying the plasmid-encoded colistin resistance gene mcr-1.

摘要

序列类型131（ST131）是肠外致病性大肠杆菌（ExPEC）中主要的大肠杆菌谱系之一，可在人类和动物中引发多种疾病，且常常表现出多重耐药性。在此，我们报告了首例来自家禽的携带质粒编码的黏菌素耐药基因mcr-1的ST131-ExPEC菌株的基因组序列。

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Genome Sequence of Avian Escherichia coli Strain IHIT25637, an Extraintestinal Pathogenic E. coli Strain of ST131 Encoding Colistin Resistance Determinant MCR-1.禽源大肠杆菌菌株IHIT25637的基因组序列，该菌株是ST131型肠外致病性大肠杆菌，携带编码黏菌素耐药决定子MCR-1。
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本文引用的文献

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Location of colistin resistance gene mcr-1 in Enterobacteriaceae from livestock and meat.家畜及肉类中肠杆菌科细菌里的黏菌素耐药基因mcr-1的定位
J Antimicrob Chemother. 2016 Aug;71(8):2340-2. doi: 10.1093/jac/dkw181. Epub 2016 May 30.
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Colistin resistance gene mcr-1 in Escherichia coli isolates from humans and retail meats, Taiwan.台湾地区从人类和零售肉类中分离出的大肠杆菌中的黏菌素耐药基因mcr-1
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Co-occurrence of extended spectrum β lactamase and MCR-1 encoding genes on plasmids.质粒上超广谱β-内酰胺酶与MCR-1编码基因的共现。
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Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015.2015 年丹麦血流感染患者和进口鸡肉中携带 mcr-1 编码质粒的耐黏菌素大肠杆菌的检测
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Extraintestinal pathogenic Escherichia coli (ExPEC) of human and avian origin belonging to sequence type complex 95 (STC95) portray indistinguishable virulence features.属于序列型复合体95（STC95）的人源和禽源肠外致病性大肠杆菌（ExPEC）具有难以区分的毒力特征。
Int J Med Microbiol. 2014 Oct;304(7):835-42. doi: 10.1016/j.ijmm.2014.06.009. Epub 2014 Jun 27.
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A new clone sweeps clean: the enigmatic emergence of Escherichia coli sequence type 131.一个新的克隆群体彻底席卷：大肠杆菌序列类型131的神秘出现。
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Foodborne Pathog Dis. 2013 Nov;10(11):916-32. doi: 10.1089/fpd.2013.1533. Epub 2013 Aug 20.