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间充质基质细胞对免疫反应的调节

Modulation of Immune Responses by Mesenchymal Stromal Cells.

作者信息

Yarygin K N, Lupatov A Yu, Sukhikh G T

机构信息

V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia.

Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia.

出版信息

Bull Exp Biol Med. 2016 Aug;161(4):561-5. doi: 10.1007/s10517-016-3461-8. Epub 2016 Sep 3.

Abstract

This concise review provides an assessment of one of the most conceptually and practically important properties of mesenchymal stromal cells, their ability to modulate immune responses, including underlying cellular and molecular mechanisms and prospects of clinical application in the treatment of autoimmune and other immunological disorders.

摘要

本简要综述评估了间充质基质细胞最具概念和实践重要性的特性之一,即其调节免疫反应的能力,包括潜在的细胞和分子机制以及在治疗自身免疫性疾病和其他免疫紊乱方面的临床应用前景。

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