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科特迪瓦、肯尼亚和莫桑比克预防母婴传播艾滋病毒的卫生设施因素及服务质量

Health facility factors and quality of services to prevent mother-to-child HIV transmission in Côte d'Ivoire, Kenya, and Mozambique.

作者信息

Rustagi Alison S, Gimbel Sarah, Nduati Ruth, Cuembelo Maria de Fatima, Wasserheit Judith N, Farquhar Carey, Gloyd Stephen, Sherr Kenneth

机构信息

1 Department of Global Health, University of Washington, Seattle, USA.

2 School of Nursing, University of Washington, Seattle, USA.

出版信息

Int J STD AIDS. 2017 Jul;28(8):788-799. doi: 10.1177/0956462416668766. Epub 2016 Sep 2.

Abstract

This study aimed to identify facility-level characteristics associated with prevention of mother-to-child HIV transmission service quality. This cross-sectional study sampled 60 health facilities in Mozambique, Côte d'Ivoire, and Kenya (20 per country). Performance score - the proportion of pregnant women tested for HIV in first antenatal care visit, multiplied by the proportion of HIV-positive pregnant women who received appropriate antiretroviral medications - was calculated for each facility using routine data from 2012 to 2013. Facility characteristics were ascertained during on-site visits, including workload. Associations between facility characteristics and performance were quantified using generalized linear models with robust standard errors, adjusting for country. Over six months, facilities saw 38,611 first antenatal care visits in total. On-site CD4 testing, Pima CD4 machine, air conditioning, and low or high (but not mid-level) patient volume were each associated with higher performance scores. Each additional first antenatal care visit per nurse per month was associated with a 4% (95% confidence interval: 1%-6%) decline in the odds that an HIV-positive pregnant woman would receive both HIV testing and antiretroviral medications. Physician workload was only modestly associated with performance. Investments in infrastructure and human resources - particularly nurses - may be critical to improve prevent mother-to-child HIV transmission service delivery and protect infants from HIV.

摘要

本研究旨在确定与预防母婴传播艾滋病服务质量相关的机构层面特征。这项横断面研究在莫桑比克、科特迪瓦和肯尼亚抽取了60家医疗机构(每个国家20家)。利用2012年至2013年的常规数据,为每个机构计算了绩效得分,即首次产前检查中接受艾滋病病毒检测的孕妇比例乘以接受适当抗逆转录病毒药物治疗的艾滋病病毒呈阳性孕妇比例。在现场访问期间确定了机构特征,包括工作量。使用具有稳健标准误差的广义线性模型对机构特征与绩效之间的关联进行量化,并对国家进行了调整。在六个月的时间里,这些机构总共进行了38,611次首次产前检查。现场CD4检测、皮马CD4机器、空调以及低或高(但不是中等)患者数量均与较高的绩效得分相关。每位护士每月额外进行的首次产前检查次数每增加一次,艾滋病病毒呈阳性孕妇同时接受艾滋病病毒检测和抗逆转录病毒药物治疗的几率就会下降4%(95%置信区间:1%-6%)。医生工作量与绩效仅有适度关联。对基础设施和人力资源(尤其是护士)的投资对于改善预防母婴传播艾滋病服务的提供以及保护婴儿免受艾滋病病毒感染可能至关重要。

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