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[缺氧对大鼠外周血红细胞分级组成的影响]

[The effect of hypoxia on the fractionated composition of erythrocytes in rat peripheral blood].

作者信息

Korobov V N, Strubitskiy I V

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1989 Apr;75(4):515-21.

PMID:2759288
Abstract

The spectrum of distribution of the rat peripheral blood erythrocytes alters during adaptation to altitude-induced hypoxia as well as under the effects of increasing concentrations of the serum lipid constituents, arterial and venous plasma factors of animals initially adapted to hypoxia, and that of 2,3-DPG. The pattern of erythrocyte distribution in the periphery seems to depend on the micromedium conditions created by organ metabolic specifics, as well as on erythrocyte intracellular factors, there- by optimizing the system of oxygen supply to organs and tissues.

摘要

在适应海拔诱导的缺氧过程中,以及在血清脂质成分浓度增加、最初适应缺氧的动物的动脉和静脉血浆因子以及2,3 -二磷酸甘油酸(2,3 - DPG)的作用下,大鼠外周血红细胞的分布谱会发生改变。外周血红细胞的分布模式似乎取决于器官代谢特性所创造的微环境条件,以及红细胞内的因素,从而优化器官和组织的氧气供应系统。

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