State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University , Lanzhou 730000, P. R. China.
Org Lett. 2016 Sep 16;18(18):4754-7. doi: 10.1021/acs.orglett.6b02516. Epub 2016 Sep 6.
A novel α-arylation of deoxybenzoins with non-prefunctionalized arenes is developed through an iron-catalyzed oxidative dehydrogenative approach. The reaction shows broad substrate scope and functional group tolerance and thus provides efficient access to synthetically useful 1,2,2-triarylethanones. A reasonable mechanism is also proposed.
通过铁催化的氧化脱氢方法，开发了一种新颖的去氧苯偶姻与非预官能化芳基的 α-芳基化反应。该反应具有广泛的底物范围和官能团耐受性，因此为合成有用的 1,2,2-三芳基乙酮提供了有效的途径。还提出了一个合理的反应机制。
