[克氏锥虫的母婴传播，墨西哥一个研究较少的健康问题：恰帕斯州病例]

[Maternal-fetal transmission of Trypanosoma cruzi, a health problem slightly studied in Mexico: case Chiapas].

作者信息

Campos-Valdez Guillermina, Canseco-Ávila Luis Miguel, González-Noriega Fernando, Alfaro-Zebadua Oscar, Nava-Medecigo Ismael Yadird, Jiménez-Cardoso Enedina

出版信息

Salud Publica Mex. 2016 Jun;58(3):378-84.

PMID:27598936

Abstract

OBJECTIVE

To determine the Trypanosoma cruzi infection prevalence in 1125 pregnant women and the transmission frequency to their children from Tapachula and Palenque, Chiapas.

MATERIALS AND METHODS

We determined the prevalence by serology tests and the transmission frequency by polymerase chain reaction (PCR) and T. cruzi reactivity capacity after 12 months.

RESULTS

Total maternal infection prevalence were 23/1 125 (2.04%), 9/600 (1.5%) were from Tapachula and 14/525 (2.6%) from Palenque. The seropositive women were between 20 and 35 years old, 31.8% have Premature Rapture of Membrane and 9.1% have history of perinatal death. The total percentage of positive newborns by PCR was 9/23 (39.13%), out of those 2/9 (22.2%) are from Tapachula and 7/14 (50%) from Palenque. The Maternal Fetal transmission frequency was. 2/9 (22.2%) in Tapachula and 1/14 (7.14%) in Palenque, all positive infants were asynthomatic.

CONCLUSION

The maternal-fetal transmission rate in Chiapas State is variable; the reason could be the maternal immunological status and T. cruzi strain.

摘要

目的

确定恰帕斯州塔帕丘拉和帕伦克1125名孕妇的克氏锥虫感染率及其向子女的传播频率。

材料与方法

我们通过血清学检测确定感染率，并通过聚合酶链反应（PCR）和12个月后的克氏锥虫反应能力确定传播频率。

结果

孕产妇总感染率为23/1125（2.04%），其中9/600（1.5%）来自塔帕丘拉，14/525（2.6%）来自帕伦克。血清反应阳性的女性年龄在20至35岁之间，31.8%有胎膜早破，9.1%有围产期死亡史。PCR检测新生儿阳性总比例为9/23（39.13%），其中2/9（22.2%）来自塔帕丘拉，7/14（50%）来自帕伦克。母婴传播频率为：塔帕丘拉2/9（22.2%），帕伦克1/14（7.14%），所有阳性婴儿均无症状。