Webster Timothy H, Wilson Sayres Melissa A
School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA.
School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA; Center for Evolution and Medicine, The Biodesign Institute at Arizona State University, Tempe, AZ 85287, USA.
Curr Opin Genet Dev. 2016 Dec;41:62-71. doi: 10.1016/j.gde.2016.08.002. Epub 2016 Sep 5.
Sex-biased demographic events have played a crucial role in shaping human history. Many of these processes affect genetic variation and can therefore leave detectable signatures in the genome because autosomal, X-linked, Y-linked, and mitochondrial DNA inheritance differ between sexes. Here, we discuss how sex-biased processes shape patterns of genetic diversity across the genome, review recent genomic evidence for sex-biased demography in modern human populations, and suggest directions for future research.
性别偏向的人口统计学事件在塑造人类历史中发挥了关键作用。其中许多过程会影响基因变异，因此由于常染色体、X 连锁、Y 连锁和线粒体 DNA 的遗传在两性之间存在差异，这些过程会在基因组中留下可检测的特征。在这里，我们讨论性别偏向的过程如何塑造全基因组的遗传多样性模式，回顾现代人类群体中性别偏向人口统计学的最新基因组证据，并提出未来研究的方向。
