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医生-药剂师协作管理:缩小社会经济血压差距。

Physician-Pharmacist Collaborative Management: Narrowing the Socioeconomic Blood Pressure Gap.

作者信息

Anderegg Maxwell D, Gums Tyler H, Uribe Liz, Coffey Christopher S, James Paul A, Carter Barry L

机构信息

From the Department of Pharmacy Practice & Science, College of Pharmacy (M.D.A., B.L.C.), Department of Biostatistics, College of Public Health (L.U., C.S.C.), and Department of Family Medicine, Roy J. and Lucille A. Carver College of Medicine (P.A.J., B.L.C.), University of Iowa; and Department of Health Outcomes & Pharmacy Practice, College of Pharmacy, University of Texas at Austin (T.H.G.).

出版信息

Hypertension. 2016 Nov;68(5):1314-1320. doi: 10.1161/HYPERTENSIONAHA.116.08043. Epub 2016 Sep 6.

Abstract

UNLABELLED

Physician-pharmacist collaboration improves blood pressure, but there is little information on whether this model can reduce the gap in healthcare disparities. This trial involved 32 medical offices in 15 states. A clinical pharmacist was embedded within each office and made recommendations to physicians and patients in intervention offices. The purpose of the present analysis was to evaluate whether the pharmacist intervention could reduce healthcare disparities by improving blood pressure in high-risk racial and socioeconomic subjects compared with the control group. The analyses in minority subjects were prespecified secondary analyses, but all other comparisons were secondary, post hoc analyses. The 9-month visit was completed by 539 patients: 345 received the intervention, and 194 were in the control group. Following the intervention, mean systolic blood pressure was found to be 7.3 mm Hg (95% confidence interval 2.4, 12.3) lower in subjects from racial minority groups who received the intervention compared with the control group (P=0.0042). Subjects with ≤12 years of education in the intervention group had a systolic blood pressure 8.1 mm Hg (95% confidence interval 3.2, 13.1) lower than the control group with lower education (P=0.0001). Similar reductions in blood pressure occurred in patients with low incomes, those receiving Medicaid, or those without insurance. This study demonstrated that a pharmacist intervention reduced racial and socioeconomic disparities in the treatment of blood pressure. Although disparities in blood pressure were reduced by the intervention, there were still nonsignificant gaps in mean systolic blood pressure when compared with intervention subjects not at risk.

CLINICAL TRIAL REGISTRATION

URL: http://clinicaltrials.gov. Unique identifier: NCT00935077.

摘要

未标注

医生与药剂师的合作可改善血压,但关于该模式能否缩小医疗保健差距的信息却很少。本试验涉及15个州的32个医疗办公室。在每个办公室安排一名临床药剂师,由其向干预办公室的医生和患者提出建议。本分析的目的是评估药剂师干预能否通过改善高危种族和社会经济背景受试者的血压,与对照组相比减少医疗保健差距。对少数族裔受试者的分析为预先设定的次要分析,但所有其他比较均为事后次要分析。539名患者完成了为期9个月的随访:345名接受干预,194名作为对照组。干预后,接受干预的少数族裔受试者的平均收缩压比对照组低7.3 mmHg(95%置信区间2.4, 12.3)(P = 0.0042)。干预组中受教育年限≤12年的受试者收缩压比受教育程度较低的对照组低8.1 mmHg(95%置信区间3.2, 13.1)(P = 0.0001)。低收入患者、接受医疗补助的患者或未参保患者的血压也有类似程度的降低。本研究表明,药剂师干预减少了血压治疗中的种族和社会经济差距。尽管干预缩小了血压差距,但与无风险的干预受试者相比,平均收缩压仍存在不显著的差距。

临床试验注册

网址:http://clinicaltrials.gov。唯一标识符:NCT00935077。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b7d/5063695/3fdb6a2f42a8/nihms810280f1.jpg

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