Fazzalari N L, Moore R J, Manthey B A, Vernon-Roberts B
Institute of Medical and Veterinary Science, Adelaide, South Australia.
J Clin Pathol. 1989 Jul;42(7):745-8. doi: 10.1136/jcp.42.7.745.
The relation between the bone histomorphometric profile of the iliac crest and regions of the proximal femur was investigated. In the proximal femur four blocks were selected, representing the subchondral principal compressive (SPC) and tensile (SPT) regions, the zone near the medial cortex in the principal compressive region (MPC), and the zone medial to the greater trochanter (MGT). Undecalcified tissue sections stained by the von Kossa silver method and counterstained with haematoxylin and eosin were used for quantitation. The SPT region was most representative of the iliac bone profile, in particular the structural parameters of mineralised bone, trabecular thickness, and trabecular spacing and resorption surface. Most parameters in the regions studied showed inconsistent and variable results when compared with those of the iliac crest. There was only a weak association, therefore, between the histomorphometric parameters of the iliac crest and the proximal femur despite the appeal of the use of the iliac biopsy specimen as a simple clinical test.
研究了髂嵴与股骨近端各区域的骨组织形态计量学特征之间的关系。在股骨近端选取了四个区域，分别代表软骨下主要压缩区（SPC）和张力区（SPT）、主要压缩区内靠近内侧皮质的区域（MPC）以及大转子内侧区域（MGT）。采用冯·科萨银染法染色并经苏木精和伊红复染的不脱钙组织切片进行定量分析。SPT区域最能代表髂骨特征，尤其是矿化骨的结构参数、小梁厚度、小梁间距和吸收表面。与髂嵴相比，所研究区域的大多数参数显示出不一致且多变的结果。因此，尽管髂骨活检标本作为一种简单的临床检测方法很有吸引力，但髂嵴与股骨近端的组织形态计量学参数之间的关联较弱。
