颅底量表（SBI）生活质量问卷的初步横断面信效度研究
Preliminary cross-sectional reliability and validity of the Skull Base Inventory (SBI) quality of life questionnaire.
作者信息
Larjani Soroush, Monteiro Eric, Witterick Ian, Vescan Allan, Zadeh Gelareh, Gentili Fred, Goldstein David P, de Almeida John R
机构信息
Department of Otolaryngology Head and Neck Surgery, University Health Network, Toronto, ON, Canada.
Department of Otolaryngology Head and Neck Surgery, Mount Sinai Hospital, Toronto, ON, Canada.
出版信息
J Otolaryngol Head Neck Surg. 2016 Sep 7;45(1):45. doi: 10.1186/s40463-016-0158-y.
BACKGROUND
The Skull Base Inventory (SBI) was developed to assess the quality of life of patients undergoing endoscopic or open approaches for anterior and central skull base pathologies. In this study, we sought to establish the discriminative and evaluative properties for this instrument.
METHODS
The SBI was administered in a cross-sectional fashion to patients who previously had skull base surgery after treatment and then again 2 weeks after completing the instrument. Internal consistency, test-retest reliability, and construct validity were determined. Four constructs were evaluated with the following a priori hypotheses: lower scores will be seen in patients with 1.malignant versus benign histology, 2.a history of radiation versus none, and those with 3.recurrences versus no recurrence, and 4.items deemed relevant versus irrelevant by respondents.
RESULTS
Fifty-two patients completed the questionnaire; 32 had endoscopic and 20 open surgeries. Internal consistency was good (>0.7 and <0.95) for all domains except one. Test-retest reliability was good (>0.70) for 38 of 41 items. Four constructs were evaluated and three were consistent with a priori hypotheses (p < 0.05). The instrument failed to confirm the hypothesis that malignant tumours are associated with poorer scores than benign.
CONCLUSIONS
The SBI demonstrated preliminary reliability and validity for discriminative use.
背景
颅底量表（SBI）旨在评估接受内镜或开放手术治疗前颅底和中颅底病变患者的生活质量。在本研究中，我们试图确定该量表的鉴别和评估特性。
方法
对既往接受过颅底手术后接受治疗的患者进行横断面调查，在完成量表2周后再次进行调查。确定内部一致性、重测信度和结构效度。对四个结构进行评估，并提出以下先验假设：1. 恶性组织学与良性组织学患者的得分较低；2. 有放疗史与无放疗史患者；3. 复发患者与未复发患者；4. 受访者认为相关与不相关的项目。
结果
52例患者完成问卷；32例行内镜手术，20例行开放手术。除一个领域外，所有领域的内部一致性良好（>0.7且<0.95）。41项中的38项重测信度良好（>0.70）。对四个结构进行评估，其中三个与先验假设一致（p<0.05）。该量表未能证实恶性肿瘤患者得分比良性肿瘤患者差的假设。
结论
SBI在鉴别使用方面显示出初步的信度和效度。
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