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Beat-to-beat cardiac repolarization lability increases during hypoxemia and arousals in obstructive sleep apnea patients.在阻塞性睡眠呼吸暂停患者中，随着低氧血症和觉醒的发生，逐搏心脏复极不稳定性增加。
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Trazodone Effects on Obstructive Sleep Apnea and Non-REM Arousal Threshold.曲唑酮对阻塞性睡眠呼吸暂停和非快速眼动睡眠觉醒阈值的影响。
Ann Am Thorac Soc. 2015 May;12(5):758-64. doi: 10.1513/AnnalsATS.201408-399OC.
2
Short-term potentiation in the control of pharyngeal muscles in obstructive apnea patients.阻塞性睡眠呼吸暂停患者咽部肌肉控制中的短期增强作用。
Sleep. 2014 Nov 1;37(11):1833-49. doi: 10.5665/sleep.4182.
3
A method for measuring and modeling the physiological traits causing obstructive sleep apnea.一种测量和建模导致阻塞性睡眠呼吸暂停的生理特征的方法。
J Appl Physiol (1985). 2011 Jun;110(6):1627-37. doi: 10.1152/japplphysiol.00972.2010. Epub 2011 Mar 24.
4
Eszopiclone increases the respiratory arousal threshold and lowers the apnoea/hypopnoea index in obstructive sleep apnoea patients with a low arousal threshold.右佐匹克隆增加了呼吸觉醒阈值，并降低了低觉醒阈值的阻塞性睡眠呼吸暂停患者的呼吸暂停/低通气指数。
Clin Sci (Lond). 2011 Jun;120(12):505-14. doi: 10.1042/CS20100588.
5
Expiratory pharyngeal narrowing during central hypocapnic hypopnea.中枢性低碳酸血症性呼吸浅慢时的呼气期咽腔狭窄
Am J Respir Crit Care Med. 2009 Feb 15;179(4):313-9. doi: 10.1164/rccm.200805-741OC. Epub 2008 Nov 21.
6
Trazodone increases arousal threshold in obstructive sleep apnoea.曲唑酮可提高阻塞性睡眠呼吸暂停的唤醒阈值。
Eur Respir J. 2008 Jun;31(6):1308-12. doi: 10.1183/09031936.00067607. Epub 2008 Feb 6.
7
Influence of wakefulness on pharyngeal airway muscle activity.觉醒对咽气道肌肉活动的影响。
Thorax. 2007 Sep;62(9):799-805. doi: 10.1136/thx.2006.072488. Epub 2007 Mar 27.
8
Role of arousals in the pathogenesis of obstructive sleep apnea.觉醒在阻塞性睡眠呼吸暂停发病机制中的作用。
Am J Respir Crit Care Med. 2004 Mar 1;169(5):623-33. doi: 10.1164/rccm.200307-1023OC. Epub 2003 Dec 18.
9
Hypercapnic ventilatory response in sleeping adults.睡眠成人的高碳酸血症通气反应
Am Rev Respir Dis. 1982 Nov;126(5):758-62. doi: 10.1164/arrd.1982.126.5.758.
10
Hypoxic ventilatory response decreases during sleep in normal men.正常男性睡眠期间的低氧通气反应会降低。
Am Rev Respir Dis. 1982 Mar;125(3):286-9. doi: 10.1164/arrd.1982.125.3.286.

Potential protective mechanism of arousal in obstructive sleep apnea.

作者信息

Deacon Naomi, Malhotra Atul

机构信息

Department of Medicine, Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, La Jolla, California, USA.

出版信息

J Thorac Dis. 2016 Jul;8(Suppl 7):S545-6. doi: 10.21037/jtd.2016.07.43.

DOI:10.21037/jtd.2016.07.43
PMID:27606089
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4990681/
Abstract
摘要