Andrade Rafaela Garcia Santos, Madeiro Fernanda, Genta Pedro Rodrigues, Lorenzi-Filho Geraldo
Sleep Laboratory, Pulmonary Division, Heart Institute (InCor), University of São Paulo, São Paulo, Brazil.
Curr Opin Pulm Med. 2016 Nov;22(6):555-62. doi: 10.1097/MCP.0000000000000318.
Continuous positive airway pressure (CPAP) delivered by nasal mask is the gold standard treatment for obstructive sleep apnea (OSA). However, oral and oronasal masks are also available. We considered experimental evidence and reviewed clinical trials that evaluated the impact of oral and oronasal mask on OSA treatment.
One recent study in 18 OSA patients that slept with a customized oronasal mask with two sealed compartments showed that the change of CPAP flow from nasal to oronasal and oral caused upper airway obstruction because of posterior displacement of the tongue demonstrated by nasoendoscopy. Oral masks use a mouthpiece that may stabilize the jaw and the tongue and have shown to be effective. However, oral masks are not widely used in clinical practice. Four out of five observational studies and all five reviewed randomized studies showed a worse performance of oronasal when compared with nasal masks. Oronasal masks were associated with higher residual apnea-hypopnea index, lower adherence, more leaks, and less satisfaction than nasal mask in the majority of the studies.
Nasal CPAP must be the first choice to treat OSA. Patients on oronasal mask should be carefully followed. VIDEO ABSTRACT.
经鼻面罩给予持续气道正压通气(CPAP)是阻塞性睡眠呼吸暂停(OSA)的金标准治疗方法。然而,也有口鼻面罩和口腔面罩可供使用。我们考量了实验证据并回顾了评估口腔面罩和口鼻面罩对OSA治疗影响的临床试验。
最近一项针对18名使用定制的带有两个密封隔室的口鼻面罩睡眠的OSA患者的研究表明,CPAP气流从鼻腔转变为口鼻和口腔时,会因鼻内镜检查显示的舌后移导致上气道阻塞。口腔面罩使用的咬嘴可能会稳定颌骨和舌头,并且已证明是有效的。然而,口腔面罩在临床实践中并未得到广泛应用。五项观察性研究中有四项以及所有五项综述的随机研究均表明,与鼻面罩相比,口鼻面罩的效果较差。在大多数研究中,口鼻面罩与更高的残余呼吸暂停低通气指数、更低的依从性、更多的漏气以及比鼻面罩更低的满意度相关。
鼻CPAP必须是治疗OSA的首选。使用口鼻面罩的患者应受到密切随访。视频摘要。