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The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening.
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The EF-hand Ca2+ Binding Domain Is Not Required for Cytosolic Ca2+ Activation of the Cardiac Ryanodine Receptor.
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Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface.
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Ryanodine receptors: structure and function.
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