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低剂量口服避孕药诱发的急性心肌梗死

Low-dose oral contraceptive-induced acute myocardial infarction.

作者信息

Aslan Abdullah Nabi, Süygün Hakan, Sivri Serkan, Keleş Telat

机构信息

a Department of Cardiology , Atatürk Education and Research Hospital , Ankara , Turkey.

b Department of Cardiology, Faculty of Medicine , Yıldırım Beyazıt University , Ankara , Turkey.

出版信息

Eur J Contracept Reprod Health Care. 2016 Dec;21(6):499-501. doi: 10.1080/13625187.2016.1225715. Epub 2016 Sep 9.

Abstract

OBJECTIVES

Since their introduction, oral contraceptives (OCs) have been associated with risk to both the venous and the arterial systems. Studies have shown that OC use is associated with a risk of venous thromboembolism, ischaemic stroke and acute myocardial infarction (MI). MI is rarely seen in patients using OCs, particularly in the absence of clinical risk factors or smoking.

CASE

We report a case of acute inferior MI in a 20-year-old non-smoker who had used a low-dose OC (3 mg drospirenone and 30 μg ethinyl estradiol) for 1 month. As far as we know, this is the youngest case of acute MI associated with a low-dose OC.

CONCLUSION

Low-dose OCs may also be responsible for acute MI even in a very young female without any cardiovascular risk factors. Therefore, the clinicians should be aware of this mortal events during follow-up of the patient using OCs.

摘要

目的

自口服避孕药(OCs)问世以来,其与静脉和动脉系统风险均相关。研究表明,使用OCs与静脉血栓栓塞、缺血性卒中和急性心肌梗死(MI)风险相关。MI在使用OCs的患者中很少见,尤其是在没有临床风险因素或吸烟的情况下。

病例

我们报告一例20岁不吸烟女性的急性下壁心肌梗死病例,该女性使用低剂量OC(3毫克屈螺酮和30微克炔雌醇)1个月。据我们所知,这是与低剂量OC相关的最年轻的急性心肌梗死病例。

结论

即使在没有任何心血管危险因素的非常年轻女性中,低剂量OCs也可能导致急性心肌梗死。因此,临床医生在对使用OCs的患者进行随访时应意识到这种致命事件。

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