低剂量复方口服避孕药致血栓性前壁心肌梗死 1 例报告。
Low dose combined oral contraceptives induced thrombotic anterior wall myocardial infarction: a case report.
机构信息
Pharmacy Department, Heart Hospital, Hamad Medical Corporation, P.O. Box 3050, Doha, Qatar.
Internal Medicine Department, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
出版信息
BMC Cardiovasc Disord. 2020 Apr 19;20(1):182. doi: 10.1186/s12872-020-01462-9.
BACKGROUND
Combined oral contraceptive pills are associated with an established risk for venous thrombosis; however, their risk for arterial thrombosis remains uncertain, especially with the development of low dose new generations of combined oral contraceptive. Arterial thrombosis is less likely to occur with the use of oral contraceptive pills in the absence of cardiovascular risk factors.
CASE PRESENTATION
We report a 35-year old female with no cardiovascular risk factors who presented with thrombotic anterior wall myocardial infarction 6 months after using a third generation low dose combined oral contraceptive pills (Marvelon; ethinylestradiol 30 mcg and desogestrel 150 mcg).
CONCLUSION
Third generation low dose combined oral contraceptives may lead to myocardial infarction in young women, even in the absence of other cardiovascular risk factors.
背景
口服避孕药与已确立的静脉血栓形成风险相关；然而，其动脉血栓形成的风险仍不确定，尤其是随着新一代低剂量复方口服避孕药的发展。在没有心血管危险因素的情况下，使用口服避孕药发生动脉血栓的可能性较小。
病例介绍
我们报告了一例 35 岁的女性，无心血管危险因素，在使用第三代低剂量复方口服避孕药（Marvelon；乙炔雌二醇 30 mcg 和去氧孕烯 150 mcg）6 个月后出现血栓性前壁心肌梗死。
结论
第三代低剂量复方口服避孕药可能导致年轻女性发生心肌梗死，即使没有其他心血管危险因素。
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