Stark C, Herkenrath P, Hollmann H, Waltz S, Becker I, Hoebing L, Semler O, Hoyer-Kuhn H, Duran I, Hero B, Hadders-Algra M, Schoenau E
University of Cologne, Children's Hospital, Germany.
J Musculoskelet Neuronal Interact. 2016 Sep 7;16(3):183-92.
to investigate feasibility, safety and efficacy of home-based side-alternating whole body vibration (sWBV) to improve motor function in toddlers with cerebral palsy (CP).
Randomized controlled trial including 24 toddlers with CP (mean age 19 months (SD±3.1); 13 boys).
14 weeks sWBV with ten 9-minute sessions weekly (non-individualized). Group A started with sWBV, followed by 14 weeks without; in group B this order was reversed. Feasibility (≥70% adherence) and adverse events were recorded; efficacy evaluated with the Gross Motor Function Measure (GMFM-66), Pediatric Evaluation of Disability Inventory (PEDI), at baseline (T0), 14 (T1) and 28 weeks (T2).
Developmental change between T0 and T1 was similar in both groups; change scores in group A and B: GMFM-66 2.4 (SD±2.1) and 3.3 (SD±2.9) (p=0.412); PEDI mobility 8.4 (SD±6.6) and 3.5 (SD±9.2) (p=0.148), respectively. In two children muscle tone increased post-sWBV. 24 children received between 67 and 140 sWBV sessions, rate of completed sessions ranged from 48 to 100% and no dropouts were observed.
A 14-week home-based sWBV intervention was feasible and safe in toddlers with CP, but was not associated with improvement in gross motor function.
探讨居家双侧交替全身振动（sWBV）改善脑瘫（CP）幼儿运动功能的可行性、安全性和有效性。
随机对照试验，纳入24名CP幼儿（平均年龄19个月（标准差±3.1）；13名男孩）。
进行14周的sWBV治疗，每周10次，每次9分钟（非个体化）。A组先进行sWBV治疗，随后14周不进行；B组顺序相反。记录可行性（依从性≥70%）和不良事件；在基线（T0）、14周（T1）和28周（T2）时，采用粗大运动功能测量量表（GMFM - 66）、儿童残疾评估量表（PEDI）评估疗效。
两组在T0和T1之间的发育变化相似；A组和B组的变化得分：GMFM - 66分别为2.4（标准差±2.1）和3.3（标准差±2.9）（p = 0.412）；PEDI运动功能分别为8.4（标准差±6.6）和3.5（标准差±9.2）（p = 0.148）。两名儿童在sWBV治疗后肌张力增加。24名儿童接受了67至140次sWBV治疗，完成治疗的比例在48%至100%之间，未观察到脱落病例。
为期14周的居家sWBV干预对CP幼儿可行且安全，但与粗大运动功能改善无关。
