Hassan Laila, MacDonald Carolyn A
University at Albany , State University of New York, Department of Physics, 1400 Washington Avenue, Albany, New York 12222, United States.
J Med Imaging (Bellingham). 2016 Jul;3(3):033504. doi: 10.1117/1.JMI.3.3.033504. Epub 2016 Aug 26.
Conventional mammography can suffer from poor contrast between healthy and cancerous tissues due to the small difference in attenuation properties. Coherent scatter slot scan imaging is an imaging technique which provides additional information and is compatible with conventional mammography. A Monte Carlo simulation of coherent scatter slot scan imaging was performed to assess its performance and provide system optimization. Coherent scatter could be exploited using a system similar to conventional slot scan mammography system with antiscatter grids tilted at the characteristic angle of cancerous tissues. System optimization was performed across several parameters, including source voltage, tilt angle, grid distances, grid ratio, and shielding geometry. The simulated carcinomas were detectable for tumors as small as 5 mm in diameter, so coherent scatter analysis using a wide-slot setup could be promising as an enhancement for screening mammography. Employing coherent scatter information simultaneously with conventional mammography could yield a conventional high spatial resolution image with additional coherent scatter information.
由于健康组织和癌组织之间的衰减特性差异较小，传统乳腺摄影可能存在组织对比度不佳的问题。相干散射狭缝扫描成像是一种能提供额外信息且与传统乳腺摄影兼容的成像技术。进行了相干散射狭缝扫描成像的蒙特卡罗模拟，以评估其性能并实现系统优化。可以使用类似于传统狭缝扫描乳腺摄影系统的装置来利用相干散射，该系统带有以癌组织特征角度倾斜的反散射栅格。对包括源电压、倾斜角度、栅格距离、栅格比和屏蔽几何形状在内的多个参数进行了系统优化。模拟结果表明，直径小至5毫米的肿瘤也能被检测到，因此使用宽狭缝设置进行相干散射分析有望作为乳腺筛查的一种增强手段。将相干散射信息与传统乳腺摄影同时使用，可以得到具有额外相干散射信息的传统高空间分辨率图像。
