Ye P, Ma D-Q, Yu G-Y, Gao Y, Peng X
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
Department of Oral Pathology, Peking University School and Hospital of Stomatology, Beijing, China.
Int J Oral Maxillofac Surg. 2017 Mar;46(3):350-354. doi: 10.1016/j.ijom.2016.08.013. Epub 2016 Sep 7.
The objective of this study was to investigate the clinical features of Kimura's disease in the head and neck region and to compare the local recurrence rate between three therapies used for the treatment of this disease. The clinicopathological information of 46 hospitalized patients suffering from Kimura's disease in the head and neck region over a 10-year period was reviewed retrospectively. All lesions were clinically observed in the head and neck region. These 46 patients underwent a total of 58 treatments; nine patients underwent multiple treatments due to local recurrence. Of the 58 treatments, 32 involved surgical excision alone, 24 involved surgical excision and postoperative low-dose radiotherapy (20-40Gy), one was a combination of ultrasound-guided core needle biopsy and radiotherapy, and one was a combination of incisional biopsy and subsequent radiotherapy. During the follow-up period, nine patients suffered 16 local recurrences. The recurrence rate of surgical excision combined with low-dose radiotherapy was much lower than that of surgical excision alone or radiotherapy alone (both P<0.05). It is concluded that Kimura's disease is a benign condition with a good prognosis, and surgical excision combined with postoperative low-dose radiotherapy is associated with the lowest local recurrence rate in the treatment of this disease.
本研究的目的是调查头颈部木村病的临床特征，并比较用于治疗该疾病的三种疗法之间的局部复发率。回顾性分析了10年间46例头颈部木村病住院患者的临床病理资料。所有病变均在头颈部临床观察到。这46例患者共接受了58次治疗；9例患者因局部复发接受了多次治疗。在58次治疗中，32次仅涉及手术切除，24次涉及手术切除及术后低剂量放疗（20 - 40Gy），1次是超声引导下粗针穿刺活检与放疗联合，1次是切开活检及后续放疗。在随访期间，9例患者出现16次局部复发。手术切除联合低剂量放疗的复发率远低于单纯手术切除或单纯放疗（均P<0.05）。结论是，木村病是一种预后良好的良性疾病，手术切除联合术后低剂量放疗在该疾病治疗中局部复发率最低。
