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多发性骨髓瘤:应对一种复杂的血癌。

Multiple myeloma: managing a complex blood cancer.

作者信息

Dowling Maura, Kelly Mary, Meenaghan Teresa

机构信息

School of Nursing and Midwifery, National University of Ireland, Galway, Ireland.

Advanced Nurse Practitioner (Haematology), Midlands Regional Hospitals, County Offaly, Ireland.

出版信息

Br J Nurs. 2016 Sep 8;25(16):S18-28. doi: 10.12968/bjon.2016.25.S18.

DOI:10.12968/bjon.2016.25.S18
PMID:27615537
Abstract

This article gives a comprehensive overview of multiple myeloma (MM), a complex blood cancer involving overproduction of plasma cells. Although MM remains incurable, patients are living longer as a result of multiple treatment options. However, MM patients are also living with a higher symptom burden. The overall aims in managing MM are therefore to control disease progression, prolong survival and improve quality of life.

摘要

本文全面概述了多发性骨髓瘤(MM),这是一种涉及浆细胞过度增殖的复杂血液癌症。尽管MM仍然无法治愈,但由于多种治疗选择,患者的生存期正在延长。然而,MM患者也承受着更高的症状负担。因此,MM治疗的总体目标是控制疾病进展、延长生存期并提高生活质量。

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1
Multiple myeloma: managing a complex blood cancer.多发性骨髓瘤:应对一种复杂的血癌。
Br J Nurs. 2016 Sep 8;25(16):S18-28. doi: 10.12968/bjon.2016.25.S18.
2
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Guidelines for the diagnosis and management of multiple myeloma 2011.2011年多发性骨髓瘤诊断与管理指南
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Guidelines for supportive care in multiple myeloma 2011.多发性骨髓瘤支持治疗指南 2011 年版
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Renal failure and multiple myeloma: pathogenesis and treatment of renal failure and management of underlying myeloma.肾衰竭与多发性骨髓瘤:肾衰竭的发病机制与治疗以及潜在骨髓瘤的管理
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Multiple myeloma.多发性骨髓瘤
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[Current approaches to treating of patients with multiple myeloma with renal failure: Questions and proofs].
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Incidence and reasons for discontinuation of first-line therapy in patients with multiple myeloma: results from a historical cohort, Brazil 2009-2020.多发性骨髓瘤患者一线治疗的中断发生率及原因:巴西2009 - 2020年历史队列研究结果
Ann Hematol. 2024 Dec;103(12):5881-5889. doi: 10.1007/s00277-024-05684-1. Epub 2024 Mar 9.
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"A lot to manage and still have some kind of a life": How multiple myeloma impacts the function and quality-of-life of Black-White patient-caregiver dyads.
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J Am Geriatr Soc. 2023 Oct;71(10):3208-3220. doi: 10.1111/jgs.18482. Epub 2023 Jun 16.
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Identification of the xenograft and its ascendant sphere-forming cell line as belonging to EBV-induced lymphoma, and characterization of the status of sphere-forming cells.鉴定异种移植瘤及其上升的成球细胞系属于EB病毒诱导的淋巴瘤,并对成球细胞的状态进行表征。
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Twice-weekly ixazomib in combination with lenalidomide-dexamethasone in patients with newly diagnosed multiple myeloma.来那度胺-地塞米松联合两周一次伊沙佐米治疗新诊断多发性骨髓瘤患者。
Br J Haematol. 2018 Jul;182(2):231-244. doi: 10.1111/bjh.15394. Epub 2018 Jun 25.