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复发性扁桃体炎和抗链球菌溶血素O滴度升高患者风湿性心脏病的患病率。

Prevalence of rheumatic heart disease in patients with recurrent tonsillitis and elevated anti-streptolysin O titers.

作者信息

Sahin M S, Yalcin M U, Kocyigit D

机构信息

Department of Otolaryngology, Hakkari State Hospital, Hakkari, Turkey.

Department of Cardiology, Hakkari State Hospital, Hakkari, Turkey.

出版信息

Int J Pediatr Otorhinolaryngol. 2016 Oct;89:133-5. doi: 10.1016/j.ijporl.2016.08.004. Epub 2016 Aug 6.

DOI:10.1016/j.ijporl.2016.08.004
PMID:27619043
Abstract

INTRODUCTION

Patients with elevated anti-streptolysin O (ASO) titers (ASOT) and recurrent tonsillitis episodes are known to be at higher risk for rheumatic heart disease (RHD). However, there is no data regarding prevalence of RHD in this high risk population. In this study, we aimed to screen ambulatory patients with elevated ASOT and recurrent tonsillitis episodes using echocardiography for identification of RHD. We hypothesized that prevalence of RHD is higher in this patient group compared to general population.

METHODS

102 patients (10.33 ± 4.01 years, 50.98% female) who were diagnosed with recurrent tonsillitis and had elevated ASOT were included this study. Echocardiographic evaluation was performed by an experienced cardiologist.

RESULTS

Echocardiographic examination revealed definite RHD in 2/102 (1.96%) patients and borderline RHD in 3/102 (2.94%) patients.

CONCLUSION

Our study demonstrates a high prevalence of RHD in patients with recurrent tonsillitis episodes and high ASOT. Screening with echocardiography is beneficial to improve the detection rates of subclinical RHD in such high-risk populations.

摘要

引言

抗链球菌溶血素O(ASO)滴度(ASOT)升高且反复出现扁桃体炎发作的患者已知患风湿性心脏病(RHD)的风险更高。然而,关于这一高危人群中RHD的患病率尚无数据。在本研究中,我们旨在使用超声心动图对ASOT升高且反复出现扁桃体炎发作的门诊患者进行筛查,以识别RHD。我们假设该患者组中RHD的患病率高于一般人群。

方法

本研究纳入了102例被诊断为反复扁桃体炎且ASOT升高的患者(年龄10.33±4.01岁,女性占50.98%)。由一位经验丰富的心脏病专家进行超声心动图评估。

结果

超声心动图检查显示,102例患者中有2例(1.96%)确诊为RHD,3例(2.94%)为临界RHD。

结论

我们的研究表明,反复扁桃体炎发作且ASOT高的患者中RHD患病率很高。在这类高危人群中,用超声心动图进行筛查有助于提高亚临床RHD的检出率。

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