Yaegaki K, Suetaka T
Shigaku. 1989 Apr;76(7):1492-500.
Volatile sulphur compounds (VSC), hydrogen sulphide, methyl mercaptan and dimethyl sulphide are by-products derived in oral cavity through putrefactive activity of microorganisms. VSC are the principal cause of physiological oral malodour. There are indications that these compounds are cytotoxic to oral tissues. Hence, it has been considered that the prevention of oral malodour has an important role in preventive dentistry. The objective of this study is to ascertain the effect of two mouthwashes, sodium azulenesulphonic acid and povidone-iodine, which are frequently used in dental clinics, on concentration of VSC in mouth air. The VSC were analyzed using VSC analysis system. VSC were determined at immediately after rince and at one, two and three hours after rince. The results indicated that neither mouthwash was very effective in controlling VSC production. No reduction in VSC was observed at one and two hour post-rinsing with sodium azulenesulphonic acid mouthwash, and only 39% reduction of total sulphur of VSC was observed at one hour following the use of the povidone-iodine containing products. However, this effect was lost within two hours post-rinsing.
挥发性硫化物（VSC）、硫化氢、甲硫醇和二甲基硫醚是口腔中微生物腐败活动产生的副产物。VSC是生理性口臭的主要原因。有迹象表明这些化合物对口腔组织具有细胞毒性。因此，人们认为预防口臭在预防牙科中具有重要作用。本研究的目的是确定牙科诊所常用的两种漱口水——磺基水杨酸蓝钠盐和聚维酮碘对口腔空气中VSC浓度的影响。使用VSC分析系统对VSC进行分析。在漱口后立即以及漱口后1小时、2小时和3小时测定VSC。结果表明，两种漱口水在控制VSC产生方面都不是非常有效。使用磺基水杨酸蓝钠盐漱口水漱口后1小时和2小时，未观察到VSC减少，使用含聚维酮碘产品后1小时，VSC总硫仅减少39%。然而，这种效果在漱口后两小时内消失。
