• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

下颌骨良性肿瘤切除术后游离移植在下颌骨重建中的应用指征:治疗方案

Indications of Free Grafts in Mandibular Reconstruction, after Removing Benign Tumors: Treatment Algorithm.

作者信息

Fariña Rodrigo, Alister Juan Pablo, Uribe Francisca, Olate Sergio, Arriagada Alvaro

机构信息

Maxillofacial Department, Hospital del Salvador, Hospital San Borja Arriarán, Dentistry School, Universidad de Chile, Santiago, Chile; Dentistry School, Universidad de La Frontera, Facultad de Medicina, Universidad de La Frontera, Maxillofacial Department of Hospital Hernán Henríquez Aravena, Temuco, Chile; and Maxillofacial Department, Hospital Base Linares, Carlos Ibáñez del Campo, Linares, Chile.

出版信息

Plast Reconstr Surg Glob Open. 2016 Aug 15;4(8):e845. doi: 10.1097/GOX.0000000000000832. eCollection 2016 Aug.

DOI:10.1097/GOX.0000000000000832
PMID:27622113
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5010336/
Abstract

BACKGROUND

Mandibular reconstruction has been the subject of much debate and research in the fields of maxillofacial surgery and head and neck surgery.

MATERIALS AND METHODS

A retrospective observational study was undertaken with 14 patients diagnosed with benign tumorous pathologies and who underwent immediate mandibular resection and reconstruction at the Hospital del Salvador Maxillofacial Surgery Unit and Dr. Rodrigo Fariña's private clinic between the years 2002 and 2012. We propose a treatment algorithm, which is previous teeth extractions in area that will be removed.

RESULTS

Fourteen patients underwent surgery, and a total of 40 dental implants were installed in 6 men and 8 women, the mean age of 33.5 (age range, 14-58 y). Reconstruction with iliac crest bone graft, and rehabilitation following this protocol (average of reconstruction was 8.7 cm), was successful with no complications at all in 12 patients. One patient had a minor complication, and the graft was partially reabsorbed because of communication of the graft with the oral cavity. This complication did not impede rehabilitation with dental implants. Another patient suffered the total loss of the graft due to infection because of dehiscence of oral mucosa and great communication with the mouth. Another iliac crest free graft reconstruction was undertaken 6 months later.

CONCLUSIONS

The scientific evidence suggests that mandibular reconstruction using free grafts following the removal of benign tumors is a biologically sustainable alternative. The critical factor to improve the prognosis of free grafts reconstruction in benign tumors is to have good quality soft tissue and avoid communication with the oral cavity. For this, it is vital to do dental extractions before removing the tumor.

摘要

背景

下颌骨重建一直是颌面外科和头颈外科领域众多争论和研究的主题。

材料与方法

对2002年至2012年间在萨尔瓦多医院颌面外科和罗德里戈·法里尼亚医生私人诊所诊断为良性肿瘤性病变并接受即刻下颌骨切除及重建的14例患者进行了一项回顾性观察研究。我们提出了一种治疗方案,即在将要切除的区域先行拔牙。

结果

14例患者接受了手术,共为6名男性和8名女性植入了40颗牙种植体,平均年龄为33.5岁(年龄范围14 - 58岁)。采用髂嵴骨移植重建,并按照该方案进行修复(平均重建长度为8.7 cm),12例患者成功且无任何并发症。1例患者出现轻微并发症,由于移植骨与口腔相通,移植骨部分被吸收。该并发症并未妨碍牙种植体修复。另1例患者因口腔黏膜裂开及与口腔大量相通导致感染,移植骨完全丧失。6个月后再次进行了游离髂嵴移植重建。

结论

科学证据表明,良性肿瘤切除后使用游离移植骨进行下颌骨重建是一种生物学上可持续的选择。提高良性肿瘤游离移植骨重建预后的关键因素是要有优质的软组织并避免与口腔相通。为此,在切除肿瘤前进行拔牙至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/30ba7dc2ae3a/gox-4-0e845-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/f20131c0df09/gox-4-0e845-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/fe79f03c679c/gox-4-0e845-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/8ef8633a492a/gox-4-0e845-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/3014fb1f055c/gox-4-0e845-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/d4693e4180b4/gox-4-0e845-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/63dbf72d65e5/gox-4-0e845-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/c3aadcc734da/gox-4-0e845-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/6c092f6f099e/gox-4-0e845-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/8a6d63b34ea8/gox-4-0e845-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/fc3f946bbae2/gox-4-0e845-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/c5a92873115c/gox-4-0e845-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/5fb25af4db22/gox-4-0e845-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/54cf3176d560/gox-4-0e845-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/7aaa3ea2f6ce/gox-4-0e845-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/637df6536fd4/gox-4-0e845-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/5e18f88c3207/gox-4-0e845-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/30ba7dc2ae3a/gox-4-0e845-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/f20131c0df09/gox-4-0e845-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/fe79f03c679c/gox-4-0e845-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/8ef8633a492a/gox-4-0e845-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/3014fb1f055c/gox-4-0e845-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/d4693e4180b4/gox-4-0e845-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/63dbf72d65e5/gox-4-0e845-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/c3aadcc734da/gox-4-0e845-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/6c092f6f099e/gox-4-0e845-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/8a6d63b34ea8/gox-4-0e845-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/fc3f946bbae2/gox-4-0e845-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/c5a92873115c/gox-4-0e845-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/5fb25af4db22/gox-4-0e845-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/54cf3176d560/gox-4-0e845-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/7aaa3ea2f6ce/gox-4-0e845-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/637df6536fd4/gox-4-0e845-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/5e18f88c3207/gox-4-0e845-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b672/5010336/30ba7dc2ae3a/gox-4-0e845-g017.jpg

相似文献

1
Indications of Free Grafts in Mandibular Reconstruction, after Removing Benign Tumors: Treatment Algorithm.下颌骨良性肿瘤切除术后游离移植在下颌骨重建中的应用指征:治疗方案
Plast Reconstr Surg Glob Open. 2016 Aug 15;4(8):e845. doi: 10.1097/GOX.0000000000000832. eCollection 2016 Aug.
2
Non-vascularised iliac crest bone graft for immediate reconstruction of lateral mandibular defect.非血管化髂嵴骨移植用于下颌骨外侧缺损的即刻重建。
Oral Maxillofac Surg. 2016 Dec;20(4):425-429. doi: 10.1007/s10006-016-0585-y. Epub 2016 Oct 10.
3
Is immediate reconstruction of the mandible with nonvascularized bone graft following resection of benign pathology a viable treatment option?良性病变切除术后采用非血管化骨移植即刻重建下颌骨是否是一种可行的治疗选择?
J Oral Maxillofac Surg. 2015 Mar;73(3):541-9. doi: 10.1016/j.joms.2014.10.019. Epub 2014 Oct 31.
4
Early bone resorption of free microvascular reanastomized bone grafts for mandibular reconstruction--a comparison of iliac crest and fibula grafts.用于下颌骨重建的游离微血管再吻合骨移植的早期骨吸收——髂嵴骨移植与腓骨移植的比较
J Craniomaxillofac Surg. 2014 Jul;42(5):e217-23. doi: 10.1016/j.jcms.2013.08.010. Epub 2013 Sep 27.
5
Rhytidectomy approach for mandibular reconstruction with microvascular free flaps after resection of mandibular benign tumors.下颌骨良性肿瘤切除术后采用微血管游离皮瓣行下颌骨重建的除皱术入路
J Oral Maxillofac Surg. 2013 Dec;71(12):2156-68. doi: 10.1016/j.joms.2013.05.009. Epub 2013 Aug 12.
6
Mandibular reconstruction using free vascularized iliac crest grafts and dental implants.使用带血管蒂游离髂嵴骨移植和牙种植体进行下颌骨重建。
Clujul Med. 2015;88(3):391-4. doi: 10.15386/cjmed-446. Epub 2015 Jul 1.
7
Immediate Transoral Allogeneic Bone Grafting for Large Mandibular Defects. Less Morbidity, More Bone. A Paradigm in Benign Tumor Mandibular Reconstruction?即刻经口异体骨移植修复下颌骨大型缺损。发病率更低,骨量更多。这是良性肿瘤下颌骨重建的一种模式?
J Oral Maxillofac Surg. 2017 Apr;75(4):828-838. doi: 10.1016/j.joms.2016.09.049. Epub 2016 Oct 6.
8
Immediate free iliac bone graft after nonsegmental mandibular resection and delayed implant placement: a case series.非节段性下颌骨切除术后即刻游离髂骨移植及延期种植体植入:病例系列
Implant Dent. 2013 Oct;22(5):438-43. doi: 10.1097/ID.0b013e31829f1ed0.
9
Autogenous bone grafts in oral implantology-is it still a "gold standard"? A consecutive review of 279 patients with 456 clinical procedures.口腔种植学中的自体骨移植——它仍是“金标准”吗?对279例患者进行456项临床手术的连续回顾。
Int J Implant Dent. 2017 Dec;3(1):23. doi: 10.1186/s40729-017-0084-4. Epub 2017 Jun 1.
10
A two-year audit of non-vascularized iliac crest bone graft for mandibular reconstruction: technique, experience and challenges.一项为期两年的非血管化髂嵴骨移植用于下颌骨重建的审计:技术、经验与挑战
J Korean Assoc Oral Maxillofac Surg. 2014 Dec;40(6):272-7. doi: 10.5125/jkaoms.2014.40.6.272. Epub 2014 Dec 26.

引用本文的文献

1
Measures of oral health-related quality of life in patients with bone graft and implant prosthetic rehabilitation at the anterior of mandible/maxilla among young and middle-aged adults: a retrospective pilot study.下颌/上颌前部接受骨移植和种植体修复的年轻和中年患者的口腔健康相关生活质量的测量:一项回顾性试点研究。
Int J Implant Dent. 2023 Nov 1;9(1):39. doi: 10.1186/s40729-023-00496-w.
2
Hydrogel: A Potential Material for Bone Tissue Engineering Repairing the Segmental Mandibular Defect.水凝胶:一种用于修复节段性下颌骨缺损的骨组织工程的潜在材料。
Polymers (Basel). 2022 Oct 5;14(19):4186. doi: 10.3390/polym14194186.
3

本文引用的文献

1
Immediate reconstruction of the mandible after resection for aggressive odontogenic tumours: a cohort study.下颌骨切除术后即刻重建用于侵袭性牙源性肿瘤:一项队列研究。
Int J Oral Maxillofac Surg. 2013 Jan;42(1):106-12. doi: 10.1016/j.ijom.2012.07.010. Epub 2012 Aug 14.
2
Benign paediatric mandibular tumours: experience in reconstruction using vascularised fibula.小儿良性下颌骨肿瘤:应用带血管腓骨重建的经验。
J Plast Reconstr Aesthet Surg. 2012 Dec;65(12):e325-31. doi: 10.1016/j.bjps.2012.07.006. Epub 2012 Aug 10.
3
Dental implant placement after mandibular reconstruction by microvascular free fibula flap: current knowledge and remaining questions.
Comparison of rhBMP-2 in Combination with Different Biomaterials for Regeneration in Rat Calvaria Critical-Size Defects.
rhBMP-2 联合不同生物材料在大鼠颅骨临界尺寸缺损再生中的比较。
Biomed Res Int. 2022 Apr 25;2022:6281641. doi: 10.1155/2022/6281641. eCollection 2022.
游离腓骨瓣微血管重建下颌骨后牙种植:当前认识与尚存问题。
Oral Oncol. 2011 Dec;47(12):1099-104. doi: 10.1016/j.oraloncology.2011.07.016. Epub 2011 Aug 27.
4
Reconstruction of the mandible using preshaped 2.3-mm titanium plates, autogenous cortical bone plates, particulate cancellous bone, and platelet-rich plasma: a retrospective analysis of 20 patients.使用预塑形2.3毫米钛板、自体皮质骨板、颗粒状松质骨和富血小板血浆重建下颌骨:20例患者的回顾性分析
J Oral Maxillofac Surg. 2010 Oct;68(10):2459-67. doi: 10.1016/j.joms.2009.12.006. Epub 2010 Jul 15.
5
Iliac crest morbidity following maxillofacial bone grafting in children: a clinical and radiographic prospective study.髂嵴骨并发症在儿童颌面骨移植中的临床和影像学前瞻性研究。
J Craniomaxillofac Surg. 2010 Jun;38(4):293-302. doi: 10.1016/j.jcms.2009.10.004. Epub 2009 Nov 27.
6
New transference technique of position of mandibular reconstructing plates using stereolithographic models.
J Oral Maxillofac Surg. 2009 Nov;67(11):2544-8. doi: 10.1016/j.joms.2009.04.086.
7
Comparison of donor-site engraftment after harvesting vascularized and nonvascularized iliac bone grafts.带血管蒂与不带血管蒂髂骨移植术后供区植入情况的比较。
J Oral Maxillofac Surg. 2009 Aug;67(8):1589-94. doi: 10.1016/j.joms.2009.04.013.
8
Nonvascularized bone grafts for segmental reconstruction of the mandible--a reappraisal.用于下颌骨节段性重建的非血管化骨移植——重新评估
J Oral Maxillofac Surg. 2009 Jul;67(7):1446-52. doi: 10.1016/j.joms.2008.12.052.
9
Quality of life evaluation for patients receiving vascularized versus nonvascularized bone graft reconstruction of segmental mandibular defects.接受血管化与非血管化骨移植重建节段性下颌骨缺损患者的生活质量评估
J Oral Maxillofac Surg. 2008 Sep;66(9):1856-63. doi: 10.1016/j.joms.2008.04.021.
10
Bone and bone graft healing.骨与骨移植愈合
Oral Maxillofac Surg Clin North Am. 2007 Nov;19(4):455-66, v. doi: 10.1016/j.coms.2007.07.008.