Ciftci Seyfettin, Nemut Tijen, Culha Mustafa Melih, Yilmaz Hasan, Ustuner Murat, Yavuz Ufuk, Ozkan Levend, Karadenizli Aynur, Turkan Sadi
Department of Urology, University of Kocaeli Medical Faculty, Kocaeli, Turkey.
Department of Health School, University of Sakarya, Sakarya, Turkey.
Int Braz J Urol. 2016 Nov-Dec;42(6):1183-1189. doi: 10.1590/S1677-5538.IBJU.2016.0061.
Aim of this study is to investigate bacterial growth on non-infected devices and compare antibiotic-coated and non-coated implants.
The charts of 71 patients who underwent revision surgeries for penile prosthesis between 1995 and 2013 were reviewed. Of those, 31 devices were antibiotic-coated prostheses, while 40 of the implants were non-coated. Swab cultures were routinely obtained from corporal, pump or reservoir site during the operation. If a bacterial biofilm was determined on the prosthesis, it was also cultured.
A total of 5 different organisms were cultured from 18 patients. Of them, 4 devices were antibiotic-coated and the other 14 were non-coated devices. Staphylococcus epidermidis was the most common organism, while Staphylococcus hominis, beta hemolitic streptococcus, Escherichia coli and Proteus mirabilis were also cultured. All patients who had positive cultures were treated with appropriate antibiotics for four weeks postoperatively. Median follow-up time was 41 months, ranging between 8 and 82 months. One prosthesis (non-coated) became clinically infected in the follow-up period with a totally different organism. Culture positivity rates of antibiotic-coated and non-coated devices were 13% and 35% respectively and the result was significant (p=0.00254).
Positive bacterial cultures are present on non-infected penile prostheses at revision surgeries in some of the patients. Antibiotic coated prostheses have much less positive cultures than non-coated devices.
本研究旨在调查未感染器械上的细菌生长情况，并比较抗生素涂层和非涂层植入物。
回顾了1995年至2013年间接受阴茎假体翻修手术的71例患者的病历。其中，31个器械为抗生素涂层假体，40个植入物为非涂层。术中常规从阴茎海绵体、泵或储液器部位获取拭子培养物。如果在假体上检测到细菌生物膜，也进行培养。
共从18例患者中培养出5种不同的微生物。其中，4个器械为抗生素涂层，另外14个为非涂层器械。表皮葡萄球菌是最常见的微生物，同时还培养出了人葡萄球菌、β溶血性链球菌、大肠杆菌和奇异变形杆菌。所有培养结果为阳性的患者术后均接受了四周的适当抗生素治疗。中位随访时间为41个月，范围在8至82个月之间。在随访期间，一个假体（非涂层）因完全不同的微生物发生了临床感染。抗生素涂层和非涂层器械的培养阳性率分别为13%和35%，结果具有显著性（p=0.00254）。
在一些患者的翻修手术中，未感染的阴茎假体上存在细菌培养阳性情况。抗生素涂层假体的培养阳性率远低于非涂层器械。
