Department of Urology, University of Alabama, Birmingham, AL, USA.
Department of Urology, Mayo Clinic, Rochester, MN, USA.
Int J Impot Res. 2020 Dec;33(8):801-807. doi: 10.1038/s41443-020-0338-1. Epub 2020 Aug 7.
The single most important factor in the reduction of penile implant infections has been the infection retardant coatings. Virtually every inflatable penile prosthesis (IPP) sold for the last 15 years in America has been coated and the device infection rate has dropped over 50% to less than 1% in experienced implanter practices. The vast majority of penile implants are contaminated with bacteria at time of surgery and the bacteria live within the implant spaces in a quiescent fashion protected by a biofilm secreted by the organisms that makes them impermeable to antibiotics or the body's defense mechanisms. Only very rarely do the bacteria cause a clinical infection. Medicine has no clue why this atypically happens. There are new recommendations for systemic prophylactic antibiotics-a testimonial to the changing face of the bacteria causing device infection. New washout solutions are being utilized and new salvage guidelines are being studied.
在降低阴茎植入物感染率方面，最重要的因素是感染抑制涂层。在过去的 15 年中，几乎每一种在美国销售的可充气阴茎假体 (IPP) 都经过了涂层处理，经验丰富的植入者的设备感染率已经下降了 50%以上，降至 1%以下。在手术时，绝大多数阴茎植入物都被细菌污染，细菌以休眠的方式存在于植入物的空间内，被生物体分泌的生物膜所保护，使其不受抗生素或身体防御机制的影响。只有极少数情况下细菌会引起临床感染。医学界不知道为什么会出现这种非典型情况。现在有系统预防性使用抗生素的新建议——这证明了导致设备感染的细菌正在发生变化。目前正在使用新的冲洗溶液，并正在研究新的挽救指南。
