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Potential endogenous inhibitor of prostaglandin synthetase in plasma: failure to inhibit cyclo-oxygenase in platelets and the gastric mucosa.

作者信息

Whittle B J

出版信息

J Pharm Pharmacol. 1978 Jul;30(7):467-8. doi: 10.1111/j.2042-7158.1978.tb13294.x.

DOI:10.1111/j.2042-7158.1978.tb13294.x
PMID:27623
Abstract
摘要

相似文献

1
Potential endogenous inhibitor of prostaglandin synthetase in plasma: failure to inhibit cyclo-oxygenase in platelets and the gastric mucosa.血浆中潜在的前列腺素合成酶内源性抑制剂：对血小板和胃黏膜中环氧化酶无抑制作用。
J Pharm Pharmacol. 1978 Jul;30(7):467-8. doi: 10.1111/j.2042-7158.1978.tb13294.x.
2
Actions of a proposed endogenous inhibitor of prostaglandin synthetase from plasma on cyclo-oxygenase activity in platelets and gastric mucosa [proceedings].一种来自血浆的前列腺素合成酶内源性抑制剂对血小板和胃黏膜中环氧化酶活性的作用[会议论文]
J Physiol. 1978 Aug;281:45P-46P.
3
Indomethacin prevents the long-lasting inhibitory effect of aspirin on human platelet cyclo-oxygenase activity.吲哚美辛可预防阿司匹林对人血小板环氧化酶活性的持久抑制作用。
Prostaglandins. 1982 Jun;23(6):787-96. doi: 10.1016/0090-6980(82)90123-x.
4
Fenflumizole: interactions with the arachidonic acid cascade.芬氟咪唑：与花生四烯酸级联反应的相互作用。
Acta Pharmacol Toxicol (Copenh). 1983 Oct;53(4):297-303. doi: 10.1111/j.1600-0773.1983.tb03426.x.
5
The inhibition of cyclo-oxygenase of rabbit platelets by aspirin is prevented by salicylic acid and by phenanthrolines.
Eur J Pharmacol. 1978 Aug 1;50(3):231-41. doi: 10.1016/0014-2999(78)90355-2.
6
Arachidonic acid metabolites and the gastro-intestinal toxicity of anti-inflammatory agents.
Prostaglandins. 1981;21 Suppl:113-8. doi: 10.1016/0090-6980(81)90126-x.
7
Platelet effects of arachidonic acid in dog blood. I. Lack of involvement of cyclo-oxygenase in the in vivo situation.花生四烯酸对犬血液中血小板的影响。I. 环氧化酶在体内情况中未起作用。
Prostaglandins. 1977 Nov;14(5):909-27. doi: 10.1016/0090-6980(77)90307-0.
8
Effect of acetaminophen and salicylate on aspirin-induced inhibition of human platelet cyclo-oxygenase.对乙酰氨基酚和水杨酸盐对阿司匹林诱导的人血小板环氧化酶抑制作用的影响。
Prostaglandins Leukot Med. 1982 Jul;9(1):109-15. doi: 10.1016/0262-1746(82)90076-2.
9
3-Phenyl-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]indole-2-carbonitrile, a potent inhibitor of prostaglandin synthetase and of platelet aggregation.3-苯基-5-[2,2,2-三氟-1-羟基-1-(三氟甲基)乙基]吲哚-2-腈，一种前列腺素合成酶和血小板聚集的强效抑制剂。
J Med Chem. 1979 Aug;22(8):948-53. doi: 10.1021/jm00194a012.
10
Short-term exposure of platelets to glucose impairs inhibition of platelet aggregation by cyclooxygenase inhibitors.血小板短期暴露于葡萄糖可损害环氧化酶抑制剂对血小板聚集的抑制作用。
Platelets. 2011;22(5):338-44. doi: 10.3109/09537104.2010.535931. Epub 2011 May 11.

引用本文的文献

1
Endogenous inhibitor of prostaglandin biosynthesis in inflammation.炎症中前列腺素生物合成的内源性抑制剂。
Agents Actions. 1980 Sep;10(4):358-60. doi: 10.1007/BF01971440.
2
Distribution of prostaglandins in gastric and duodenal mucosa of healthy subjects and duodenal ulcer patients: effects of aspirin and paracetamol.健康受试者和十二指肠溃疡患者胃及十二指肠黏膜中前列腺素的分布：阿司匹林和对乙酰氨基酚的影响
Gut. 1981 Apr;22(4):283-9. doi: 10.1136/gut.22.4.283.
3
Prevention of ethanol and aspirin-induced gastric mucosal lesions by paracetamol and salicylate in rats: role of endogenous prostaglandins.
对乙酰氨基酚和水杨酸盐对大鼠乙醇和阿司匹林所致胃黏膜损伤的预防作用：内源性前列腺素的作用
Gut. 1982 Jun;23(6):536-40. doi: 10.1136/gut.23.6.536.
4
Role of locally generated prostaglandins in adaptive gastric cytoprotection.局部产生的前列腺素在适应性胃细胞保护中的作用。
Dig Dis Sci. 1982 Nov;27(11):967-71. doi: 10.1007/BF01391740.
5
Stimulation of gastric prostaglandin synthesis by refeeding in the rat. Role in protection of gastric mucosa from damage.大鼠再喂养对胃前列腺素合成的刺激作用。在保护胃黏膜免受损伤中的作用。
Dig Dis Sci. 1984 Apr;29(4):330-5. doi: 10.1007/BF01318519.
6
Role of prostaglandin and thromboxane biosynthesis in gastric necrosis produced by taurocholate and ethanol.前列腺素和血栓素生物合成在牛磺胆酸盐和乙醇所致胃坏死中的作用
Dig Dis Sci. 1983 Feb;28(2):154-60. doi: 10.1007/BF01315145.
7
Aspirin-induced gastric ulcers in cats. Prevention by prostacyclin.猫阿司匹林诱导的胃溃疡。前列环素的预防作用。
Dig Dis Sci. 1981 Nov;26(11):1003-12. doi: 10.1007/BF01314763.
8
Phospholipase inhibition and prostacyclin generation by gastric muscularis and mucosa layers.胃肌层和黏膜层对磷脂酶的抑制作用及前列环素的生成
Agents Actions. 1986 Aug;18(5-6):535-7. doi: 10.1007/BF01964960.
9
Somatostatin inhibits gastric acid secretion after gastric mucosal prostaglandin synthesis inhibition by indomethacin in man.在人体中，生长抑素在吲哚美辛抑制胃黏膜前列腺素合成后可抑制胃酸分泌。
Gut. 1985 Nov;26(11):1189-91. doi: 10.1136/gut.26.11.1189.
10
Healing of acetic acid-induced gastric ulcer and gastric mucosal PGI2 level in rats.
Dig Dis Sci. 1990 Jan;35(1):80-5. doi: 10.1007/BF01537227.