Jewer D D, Boyd J B, Manktelow R T, Zuker R M, Rosen I B, Gullane P J, Rotstein L E, Freeman J E
Division of Plastic Surgery, St. John's Health Sciences Center, Toronto, Ontario, Canada.
Plast Reconstr Surg. 1989 Sep;84(3):391-403; discussion 404-5.
Sixty vascularized iliac crest free-tissue transfers were used for oromandibular reconstruction, 46 as osteocutaneous and 14 as osseous flaps. Forty-one patients had preoperative radiotherapy, and 8 had failed previous attempts at reconstruction. Forty-nine of the 60 reconstructions were carried out primarily, most commonly following ablative surgery for radiorecurrent squamous carcinoma. Ages ranged from 19 to 85 years, and follow-up ranged from 2 months to 5 years. Flap survival was 95 percent. Eight-six percent of patients returned to their previous activities. There were 2 perioperative deaths, and 31 patients were alive at follow-up. Horizontal defects from 5 to 16 cm were reconstructed, and in 22 patients, both oral lining and skin coverage were replaced. Radiographic evidence of bone union was noted in 96 percent of synostoses, and clinical union was seen in all but one patient. One patient required bilateral hemimandibular reconstructions for sequential primaries at different operative sittings. Functional and cosmetic results were generally satisfactory and were excellent in bone-only reconstructions. Several surgical principles evolved to minimize bulk and eliminate the need for intermaxillary fixation or external fixation postoperatively. To improve results in large or more lateral through-and-through defects, an accessory pectoralis musculocutaneous flap proved advantageous. Cosmetic and functional results depend largely on three factors: the extent of the surgery, the leanness of the patient, and his or her position on the surgical learning curve.
60例带血管蒂的游离髂嵴组织瓣被用于口腔颌面部重建,其中46例为骨皮瓣,14例为骨瓣。41例患者术前行放疗,8例既往重建手术失败。60例重建手术中49例为一期手术,最常见于放射性复发性鳞状细胞癌切除术后。患者年龄范围为19至85岁,随访时间为2个月至5年。皮瓣存活率为95%。86%的患者恢复了术前活动。围手术期死亡2例,随访时31例患者存活。重建了5至16厘米的水平缺损,22例患者的口腔黏膜和皮肤覆盖均得到修复。96%的骨融合有影像学骨愈合证据,除1例患者外均可见临床愈合。1例患者因不同手术部位的连续原发性肿瘤需要双侧半下颌骨重建。功能和美容效果总体令人满意,仅骨重建效果极佳。为尽量减少组织体积并消除术后颌间固定或外固定的必要性,形成了几条手术原则。为改善大型或更外侧贯通性缺损的治疗效果,辅助胸大肌肌皮瓣被证明具有优势。美容和功能效果很大程度上取决于三个因素:手术范围、患者的消瘦程度以及其在手术学习曲线上的位置。