Gvirts Hila Z, Mayseless Naama, Segev Aviv, Lewis D Yael, Feffer Kfir, Barnea Yael, Bloch Yuval, Shamay-Tsoory Simon G
1 Department of Psychology, University of Haifa, Haifa, Israel.
2 Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
J Psychopharmacol. 2017 May;31(5):599-605. doi: 10.1177/0269881116667703. Epub 2016 Sep 13.
In recent years the use of psychostimulants for cognitive enhancement in healthy individuals with no psychiatric disorders has been on the rise. However, it is still unclear whether psychostimulants improve certain cognitive functions at the cost of others, and how these psychostimulants interact with individual personality differences. In the current study, we investigated whether the effect of one common stimulant, methylphenidate (MPH), on creativity is associated with novelty seeking. Thirty-six healthy adults, without attention-deficit hyperactivity disorder (ADHD) symptomology, were assigned randomly in a double-blind fashion to receive MPH or placebo. We found that the effect of MPH on creativity was dependent on novelty-seeking (NS) personality characteristics of the participants. MPH increased creativity in individuals with lower NS, while it reduced creativity levels in individuals with high NS. These findings highlight the role of the dopaminergic system in creativity, and indicate that among healthy individuals NS can be seen as a predictor of the effect of MPH on creativity.
近年来，在没有精神疾病的健康个体中，使用精神兴奋剂来增强认知能力的情况呈上升趋势。然而，目前仍不清楚精神兴奋剂是否以牺牲其他认知功能为代价来改善某些认知功能，以及这些精神兴奋剂如何与个体的人格差异相互作用。在本研究中，我们调查了一种常见兴奋剂哌甲酯（MPH）对创造力的影响是否与寻求新奇性有关。36名没有注意力缺陷多动障碍（ADHD）症状的健康成年人被随机双盲分配接受MPH或安慰剂。我们发现，MPH对创造力的影响取决于参与者的寻求新奇性（NS）人格特征。MPH提高了低NS个体的创造力，而降低了高NS个体的创造力水平。这些发现突出了多巴胺能系统在创造力中的作用，并表明在健康个体中，NS可被视为MPH对创造力影响的一个预测指标。
