Yalınçetin Berna, Ulaş Halis, Var Levent, Binbay Tolga, Akdede Berna Binnur, Alptekin Köksal
Dokuz Eylul University, Department of Neuroscience, Izmir, Turkey.
Dokuz Eylul University, School of Medicine, Department of Psychiatry, Izmir, Turkey.
Compr Psychiatry. 2016 Oct;70:98-104. doi: 10.1016/j.comppsych.2016.07.001. Epub 2016 Jul 4.
The aim of this cross-sectional study is to examine the relation of formal thought disorder (FTD) with symptomatic remission (SR) and social functioning in patients with schizophrenia.
The study was carried out with a sample consisting of 117 patients diagnosed with schizophrenia according to DSM-IV. The patients were assessed with the Positive and Negative Syndrome Scale (PANSS), the Thought and Language Index (TLI), and the Personal and Social Performance Scale (PSP). We used logistic regression in order to determine the relation between FTD and SR and linear regression to identify the strength of association between FTD and social functioning.
Logistic regression analysis revealed that poverty of speech (odds ratio: 1.47, p<0.01) and peculiar logic (odds ratio: 1.66, p=0.01) differentiated the remitted patients from the non-remitted ones. Linear regression analysis showed that the PSP total score was associated with poverty of speech and peculiar logic items of the TLI (B=-0.23, p<0.01, B=-0.24, p=0.01, respectively).
Our findings suggest that poverty of speech and peculiar logic are the specific domains of FTD which are related to both SR status and social functioning in patients with schizophrenia.
本横断面研究旨在探讨精神分裂症患者形式思维障碍（FTD）与症状缓解（SR）及社会功能之间的关系。
该研究以117例根据《精神疾病诊断与统计手册》第四版（DSM-IV）诊断为精神分裂症的患者为样本。采用阳性与阴性症状量表（PANSS）、思维与语言指数（TLI）及个人和社会功能量表（PSP）对患者进行评估。我们使用逻辑回归来确定FTD与SR之间的关系，并使用线性回归来确定FTD与社会功能之间关联的强度。
逻辑回归分析显示，言语贫乏（比值比：1.47，p<0.01）和奇特逻辑（比值比：1.66，p=0.01）可区分缓解患者与未缓解患者。线性回归分析表明，PSP总分与TLI的言语贫乏和奇特逻辑项目相关（分别为B=-0.23，p<0.01；B=-0.24，p=0.01）。
我们的研究结果表明，言语贫乏和奇特逻辑是FTD的特定领域，与精神分裂症患者的SR状态和社会功能均相关。
