希腊精神分裂症患者样本中个人与社会表现量表（PSP）与阳性和阴性症状量表（PANSS）之间的相关性。
Correlation between the Personal and Social Performance scale (PSP) and the Positive and Negative Syndrome Scale (PANSS) in a Greek sample of patients with schizophrenia.
作者信息
Jelastopulu Eleni, Giourou Evangelia, Merekoulias Giorgos, Mestousi Angeliki, Moratis Eleftherios, Alexopoulos Evangelos C
机构信息
Department of Public Health, School of Medicine, University of Patras, Rio-Patras GR-26500, Greece.
出版信息
BMC Psychiatry. 2014 Jul 8;14:197. doi: 10.1186/1471-244X-14-197.
BACKGROUND
Psychosocial dysfunction is one of schizophrenia's core features, often leading to a deprecation of independent living and significant failure to maintain a competent quality of life. Cognitive and occupational performance as well as psychosocial functioning is moreover recognized as determinants of treatment response. Therefore, the elaboration of measures regarding social performance besides scales that assess psychopathology is essential. The Personal and Social Performance (PSP) scale has been found to be as much valid as reliable for assessing social functioning in the acute and stable stage of schizophrenia. The aim of this study was to estimate the correlation between the PSP and Positive and Negative Syndrome Scale (PANSS) (convergent validity) in patients with schizophrenia during routine clinical practice.
METHODS
A longitudinal study with a six-month follow-up is presented. Correlation between the PSP scale and the Positive and Negative Syndrome Scale (PANSS) was conducted in a Greek sample of 2010 patients with schizophrenia in outpatient setting in two successive visits. PANSS and PSP scales were used for the assessment of psychopathological symptoms and social and personal functioning.
RESULTS
The PSP subscales scores were well correlated with each other with Spearman correlation coefficients (r) ranging from 0.56 to 0.76 on both visits in three out of the four main areas, whereas in the category of "disturbing and aggressive behavior" the correlations were lower but still significant. Furthermore, total PSP score showed high association to PANSS total score in the first (r = -0.59) as well as in the second visit (r = -0.50). Regression analysis showed that one point decrease of PANSS's total score is associated with a 0.42 points increase on the PSP scale. PSP and PANSS scales exhibited high convergent validity.
CONCLUSIONS
The PSP could provide additional valuable information in the assessment of schizophrenia related social functioning and treatment response.
背景
社会心理功能障碍是精神分裂症的核心特征之一，常常导致独立生活能力下降以及无法有效维持有质量的生活。此外，认知和职业表现以及社会心理功能被认为是治疗反应的决定因素。因此，除了评估精神病理学的量表外，制定有关社会表现的测量方法至关重要。个人和社会表现（PSP）量表已被发现对于评估精神分裂症急性和稳定期的社会功能既有效又可靠。本研究的目的是在常规临床实践中评估精神分裂症患者的PSP量表与阳性和阴性症状量表（PANSS）之间的相关性（收敛效度）。
方法
呈现一项为期六个月随访的纵向研究。在希腊的一个门诊环境中，对2010例精神分裂症患者进行了连续两次访视，评估了PSP量表与阳性和阴性症状量表（PANSS）之间的相关性。PANSS和PSP量表用于评估精神病理症状以及社会和个人功能。
结果
在四次主要领域中的三次中，两次访视时PSP子量表得分彼此之间均具有良好的相关性，Spearman相关系数（r）范围为0.56至0.76，而在“干扰和攻击行为”类别中，相关性较低但仍具有显著性。此外，PSP总分在第一次访视时（r = -0.59）以及第二次访视时（r = -0.50）均与PANSS总分高度相关。回归分析表明，PANSS总分每降低1分，PSP量表得分增加0.42分。PSP和PANSS量表表现出较高的收敛效度。
结论
PSP在评估精神分裂症相关的社会功能和治疗反应方面可提供额外的有价值信息。
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