Yoon Lara, Clarke Hillyer Grace, Chen Ling, Hu Jim C, Neugut Alfred I, Hershman Dawn L, Wright Jason D
a Department of Epidemiology , Mailman School of Public Health, Columbia University , New York , New York , USA.
b Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center , New York , New York , USA.
Cancer Invest. 2016 Sep 13;34(8):408-14. doi: 10.1080/07357907.2016.1221078.
Venous thromboembolic disease is a major cause of morbidity in cancer patients. The Perspective database was used to identify patients with solid tumors and a diagnosis of VTE from 2006 to 2012. We examined use of IVC filters, thrombolysis, and thrombectomy. Among 32,545 patients, 23.1% received an IVC filter, 1.9% thrombolytic therapy, and 0.4% underwent thrombectomy. Use of IVC filters decreased between 2006 and 2012 (23.4% to 21.2%, p = 0.012). Older patients, uninsured patients, Hispanics, and those with more comorbidities were more likely to undergo filter placement while patients at rural hospitals were less likely to receive an IVC filter (p < 0.05 for all).
静脉血栓栓塞性疾病是癌症患者发病的主要原因。利用“透视”数据库识别出2006年至2012年期间患有实体瘤且诊断为VTE的患者。我们研究了下腔静脉滤器、溶栓和血栓切除术的使用情况。在32545名患者中，23.1%接受了下腔静脉滤器植入，1.9%接受了溶栓治疗，0.4%接受了血栓切除术。2006年至2012年期间下腔静脉滤器的使用有所减少（从23.4%降至21.2%，p = 0.012）。老年患者、未参保患者、西班牙裔以及合并症较多的患者更有可能接受滤器植入，而农村医院的患者接受下腔静脉滤器的可能性较小（所有p值均<0.05）。
