Hussain Aneela N, Alkhenizan Abdullah, McWalter Patricia, Qazi Nusrat, Alshmassi Amal, Farooqi Samina, Abdulkarim Ahmed
Department of Family Medicine and Polyclinic, King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia.
J Family Community Med. 2016 Sep-Dec;23(3):145-50. doi: 10.4103/2230-8229.189107.
Rising incidence of human papillomavirus (HPV) infection and cervical cancer can be reduced by effective vaccination. Saudi Food and Drug Administration approved prophylactic HPV vaccine in 2010 for females of 11-26 years.
To determine the awareness of HPV infection, its health sequel and the attitude and barriers to the acceptance of HPV vaccine by young women in Saudi Arabia. Dynamics influencing the decision of patients and parents regarding vaccination were assessed to foster effective and strategically focused interventions.
All patients of Family Medicine department, King Faisal Specialist Hospital and Research Center, Riyadh were invited to participate in this study from January 2012 to June 2014. A culturally sensitive and specially designed questionnaire was administered using an interview-based model to assess the knowledge, perception, and associated sociodemographic factors of HPV.
A total of 325 patients participated as per the inclusion criteria: 87.4% were Saudis, 53.5% had university or higher education and 65.2% were adolescents (age 11-19 years). The questionnaire was answered by participants (50.8%) or guardians (49.2%). About 34.5% of the population was aware of HPV infection, and 27.4% were aware of its relation with cervical cancer. However, awareness of the HPV vaccine, perception of its prevention of cervical cancer and other HPV-related disease was relatively low (32.3%), Saudis (29.9%) versus non-Saudis (48.8%) (P = 0.016). More guardians (41.2%) were aware of the HPV vaccine and its impact than participants (27.9%) (P = 0.01). Higher educational background (43.1%) increased the knowledge of HPV compared to less than high school education (24.5%) (odds ratio: 2.33; 95% confidence interval: 1.44-3.76). Nearly 64.3% of participants agreed, and 35.7% refused to receive the HPV vaccine.
Knowledge and perception of HPV infection as an sexually transmitted infections and its vaccine was significantly low in this cohort of patients. Higher age and educational levels directly correlated with increased knowledge of HPV infection and its complications. It is recommended that awareness should be raised, and access to HPV vaccination increased to help reduce the health care burden of HPV sequelae in the Kingdom.
有效的疫苗接种可降低人乳头瘤病毒（HPV）感染率及宫颈癌发病率。沙特食品药品管理局于2010年批准了预防性HPV疫苗，适用于11至26岁的女性。
确定沙特阿拉伯年轻女性对HPV感染、其健康后果以及接受HPV疫苗的态度和障碍。评估影响患者及其父母疫苗接种决策的动态因素，以促进有效且具有战略重点的干预措施。
2012年1月至2014年6月，邀请利雅得法赫德国王专科医院及研究中心家庭医学科的所有患者参与本研究。采用基于访谈的模式，使用一份对文化敏感且专门设计的问卷，以评估HPV的知识、认知及相关社会人口学因素。
共有325名患者符合纳入标准参与研究：87.4%为沙特人，53.5%拥有大学及以上学历，65.2%为青少年（11至19岁）。问卷由参与者（50.8%）或监护人（49.2%）回答。约34.5%的人群知晓HPV感染，27.4%知晓其与宫颈癌的关系。然而，对HPV疫苗的知晓率、对其预防宫颈癌及其他HPV相关疾病的认知相对较低（32.3%），沙特人（29.9%）低于非沙特人（48.8%）（P = 0.016）。知晓HPV疫苗及其影响的监护人（41.2%）多于参与者（27.9%）（P = 0.01）。与高中以下学历（24.5%）相比，高等教育背景（43.1%）可增加HPV知识（优势比：2.33；95%置信区间：1.44 - 3.76）。近64.3%的参与者同意，35.7%拒绝接种HPV疫苗。
在这组患者中，对作为性传播感染的HPV感染及其疫苗的知识和认知显著较低。年龄和教育水平越高，对HPV感染及其并发症的知识了解越多。建议提高认识，并增加HPV疫苗接种机会，以帮助减轻沙特王国HPV后遗症的医疗负担。
