Pantiora Eirini V, Kontis Elissaios A, Michalaki Vasiliki, Primetis Elias, Vezakis Antonios, Polydorou Andreas, Fragulidis Georgios P
2nd Department of Surgery, ARETAIEIO Hospital, National and Kapodistrian University of Athens School of Medicine.
Department of Oncology, ARETAIEIO Hospital, National and Kapodistrian University of Athens School of Medicine.
Cureus. 2016 Aug 1;8(8):e717. doi: 10.7759/cureus.717.
Positron emission tomography-computed tomography (PET/CT) improves the diagnostic interpretation of fluorine-18 fluorodeoxyglucose (18F-FDG ) PET and CT in oncologic patients and has an impact on both diagnostic and therapeutic aspects of patient management. However, false positive findings from the PET/CT imaging should be taken into consideration as they mislead physicians into improper therapeutic actions. We present a 48-year-old female patient with a history of left colectomy for colorectal cancer and subsequent liver metastasectomy. After one year of follow-up, she presented with a highly suspicious lesion in the liver, which was confirmed on PET/CT as a metastatic liver tumor. Consequently, the patient underwent surgical excision of the tumor, and the definitive histological diagnosis showed a granulomatous tissue with giant cells and foreign body tissue reaction. Based on this report, we briefly review the dangerous pitfalls from radiological and PET/CT imaging concerning the preoperative diagnostic workup examination, as they may significantly alter the treatment plan in oncologic patients.
正电子发射断层扫描-计算机断层扫描(PET/CT)改善了氟-18氟脱氧葡萄糖(18F-FDG)PET和CT在肿瘤患者中的诊断解读,并且对患者管理的诊断和治疗方面都有影响。然而,PET/CT成像的假阳性结果应予以考虑,因为它们会误导医生采取不当的治疗行动。我们报告一名48岁女性患者,有因结直肠癌行左半结肠切除术及随后肝转移瘤切除术的病史。随访一年后,她肝脏出现一个高度可疑病变,PET/CT证实为肝转移瘤。因此,患者接受了肿瘤手术切除,最终组织学诊断显示为伴有巨细胞的肉芽肿组织和异物组织反应。基于本报告,我们简要回顾了术前诊断检查中放射学和PET/CT成像的危险陷阱,因为它们可能会显著改变肿瘤患者的治疗方案。