Lisboa Maria, Domingues Isabel, Pamplona Jaime, Barata Pedro, Morgado Joana, Brotas Vítor
Ophthalmology Department, Centro Hospitalar de Lisboa Central EPE, Lisbon, Portugal.
Neuroradiology Department, Centro Hospitalar de Lisboa Central EPE, Lisbon, Portugal.
GMS Ophthalmol Cases. 2014 Jan 8;4:Doc01. doi: 10.3205/oc000014. eCollection 2014.
To describe a clinical case and literature review of Whipple disease.
A 65-year-old male with bilateral decreased visual acuity for 3 weeks as well as bilateral hypoacusia, vertigo, disequilibrium, headache and decreased strength in the right upper limb for 4 months. The clinical work-up revealed a bilateral panuveitis and an ischemic cerebellar stroke.
The diagnosis of Whipple disease was confirmed by histopathological analysis of adenopathy. The patient was treated with cortico-antibiotic therapy with significant clinical improvement.
Although rare, Whipple disease is potentially fatal if left untreated, it must be always be taken into consideration before any panuveitis of an unknown cause, even in the absence of gastrointestinal symptoms.
描述一例惠普尔病的临床病例并进行文献综述。
一名65岁男性，双眼视力下降3周，伴有双耳听力减退、眩晕、平衡失调、头痛以及右上肢力量减弱4个月。临床检查发现双侧全葡萄膜炎和缺血性小脑卒中。
通过淋巴结组织病理学分析确诊为惠普尔病。患者接受皮质类固醇抗生素治疗后临床症状显著改善。
尽管惠普尔病罕见，但如果不治疗可能会致命，对于任何不明原因的全葡萄膜炎，即使没有胃肠道症状，也必须始终考虑到该病。
