Pinxten Isabel, Stalmans Peter
University Hospitals Leuven, Belgium.
GMS Ophthalmol Cases. 2014 Jul 15;4:Doc05. doi: 10.3205/oc000018. eCollection 2014.
Radial optic neurotomy (RON) was first described by Opremcak as a treatment for patients with central retinal vein occlusion (CRVO). The most common cause of visual loss in patients with optic disc drusen is nonarteritic anterior ischemic optic neuropathy (NAION). The pathogenesis of nonarteritic anterior ischemic optic neuropathy associated with optic disc drusen is assumed to be similar to the compartment-like syndrome described by Opremcak in the case of central retinal vein occlusion.
An 82-year-old male with bilateral optic disc drusen presented with bilateral visual loss and severe visual field defects consistent with nonarteritic anterior ischemic optic neuropathy. A radial optic neurotomy was performed to treat the most affected eye. Postoperatively, significant and persistent improvement of visual acuity and improved automated perimetry were observed in the operated eye.
Optic nerve head decompression by radial optic neurotomy could be a treatment option in patients with nonarteritic anterior ischemic optic neuropathy associated with optic disc drusen and severe visual field defects.
放射状视神经切开术(RON)最早由奥普雷姆卡描述为治疗视网膜中央静脉阻塞(CRVO)患者的一种方法。视盘玻璃疣患者视力丧失的最常见原因是非动脉性前部缺血性视神经病变(NAION)。与视盘玻璃疣相关的非动脉性前部缺血性视神经病变的发病机制被认为与奥普雷姆卡在视网膜中央静脉阻塞病例中描述的间隔样综合征相似。
一名82岁双侧视盘玻璃疣男性患者出现双侧视力丧失和严重视野缺损,符合非动脉性前部缺血性视神经病变。对受影响最严重的眼睛进行了放射状视神经切开术。术后,患眼视力显著且持续改善,自动视野检查结果也有所改善。
对于与视盘玻璃疣相关且伴有严重视野缺损的非动脉性前部缺血性视神经病变患者,放射状视神经切开术进行视神经乳头减压可能是一种治疗选择。