Monti J M, Vignale R, Monti D
Department of Pharmacology, School of Medicine, Clinic Hospital, Montevideo, Uruguay.
Sleep. 1989 Aug;12(4):309-14. doi: 10.1093/sleep/12.4.309.
The number of scratching episodes and average frequency with which they started during each sleep stage as well as the effects of nighttime pruritus on objective sleep parameters in nine children with atopic dermatitis were assessed in the sleep laboratory. Scratching episodes occurred during rapid eye movement (REM) sleep and non-REM (NREM) sleep. The largest average frequency corresponded to stage 1, followed by stage 2, REM sleep, stage 4, and stage 3. Sleep maintenance was markedly altered. Total sleep time decrease was related mainly to smaller amounts of stage 4 NREM sleep. REM sleep percentage of total sleep time was increased as compared with normal children of the same age. Furthermore, in six of nine patients REM sleep latency was found to be decreased.
在睡眠实验室中，对9名特应性皮炎患儿的抓挠发作次数、每个睡眠阶段开始抓挠的平均频率以及夜间瘙痒对客观睡眠参数的影响进行了评估。抓挠发作发生在快速眼动（REM）睡眠和非快速眼动（NREM）睡眠期间。平均频率最高的是第1阶段，其次是第2阶段、REM睡眠、第4阶段和第3阶段。睡眠维持明显改变。总睡眠时间减少主要与第4阶段NREM睡眠量减少有关。与同年龄的正常儿童相比，REM睡眠占总睡眠时间的百分比增加。此外，9名患者中有6名的REM睡眠潜伏期缩短。
