Savin J A, Paterson W D, Oswald I, Adam K
Br J Dermatol. 1975 Sep;93(3):297-302. doi: 10.1111/j.1365-2133.1975.tb06495.x.
Fifteen patients with a variety of itching skin diseases (atopic eczema, dermatitis herpetiformis, lichen planus, urticaria and psoriasis) have been studied in the sleep laboratory. Recordings were made of all-night electroencephalogram, electro-oculogram, submental electromyogram, and muscle potentials from both forearms. Bouts of scratching during orthodox (NREM) sleep occurred more frequently in stages 1 and 2 than in stages 3 and 4. The frequency in paradoxial (REM) sleep was close to that in stage 2 sleep. This pattern was similar for all the diseases studied and seems to be related to the physiology of the sleep stages rather than to the skin diseases themselves. The mean duration of the bouts of scratching was not related to the sleep stage in which they started.
15名患有各种瘙痒性皮肤病（特应性湿疹、疱疹样皮炎、扁平苔藓、荨麻疹和银屑病）的患者在睡眠实验室接受了研究。记录了整夜的脑电图、眼电图、颏下肌电图以及双侧前臂的肌肉电位。在正统（非快速眼动）睡眠期间，抓挠发作在第1和第2阶段比在第3和第4阶段更频繁。在异相（快速眼动）睡眠中的频率与第2阶段睡眠相近。对于所有研究的疾病，这种模式都是相似的，似乎与睡眠阶段的生理状况有关，而非与皮肤病本身相关。抓挠发作的平均持续时间与发作起始的睡眠阶段无关。
