Ishiguro Takashi, Takayanagi Noboru, Baba Yuri, Kagiyama Naho, Miyamoto Takashi, Mutoh Makoto, Shimizu Yoshihiko, Sugita Yutaka
Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan.
Intern Med. 2016;55(18):2679-84. doi: 10.2169/internalmedicine.55.6855. Epub 2016 Sep 15.
Pulmonary tumor embolism (PTE) and intravascular lymphoma cause rapidly progressive deterioration and an antemortem diagnosis is difficult. The usefulness of pulmonary microvascular cytology (PMC) in the diagnosis of these disorders has been reported in sporadic case reports. We retrospectively evaluated the records of 7 patients with tumor cells in the pulmonary microvasculature (4 with PTE and 3 with malignant lymphoma) who underwent pulmonary microvascular cytology. Two of the 4 patients with PTE and 2 of the 3 patients with malignant lymphoma (all 3 had intravascular metastasis) had positive PMC results. These findings suggested that PMC may be useful in the diagnosis of these disorders.
肺肿瘤栓塞（PTE）和血管内淋巴瘤可导致病情迅速进展恶化，生前诊断困难。散发病例报告中已报道了肺微血管细胞学（PMC）在这些疾病诊断中的作用。我们回顾性评估了7例肺微血管中存在肿瘤细胞（4例PTE和3例恶性淋巴瘤）并接受肺微血管细胞学检查患者的记录。4例PTE患者中有2例，3例恶性淋巴瘤患者中有2例（3例均有血管内转移）PMC结果呈阳性。这些发现提示PMC可能有助于这些疾病的诊断。
