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纵隔未分化肉瘤患者因肿瘤栓塞导致肾动脉闭塞和急性肾损伤,经血管内介入治疗诊断和治疗。

Tumor Embolism as a Cause of Renal Artery Occlusion and Acute Kidney Injury Diagnosed and Treated with Endovascular Intervention in a Patient with Mediastinal Undifferentiated Sarcoma.

机构信息

Department of Respiratory Medicine, Japan Community Health Care Organization Kyushu Hospital, Japan.

Department of Radiology, Japan Community Health Care Organization Kyushu Hospital, Japan.

出版信息

Intern Med. 2021 Jun 15;60(12):1907-1910. doi: 10.2169/internalmedicine.6249-20. Epub 2021 Jan 15.

DOI:10.2169/internalmedicine.6249-20
PMID:33456039
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8263193/
Abstract

A 72-year-old man presented with back pain due to a mass in the left posterior mediastinum that had surrounded and partly infiltrated the descending aorta. Mediastinal undifferentiated sarcoma was diagnosed. After the diagnosis, sudden anuria was observed. Contrast-enhanced computed tomography revealed an enhancement defect at the origins of the bilateral renal arteries. He received catheter-directed thrombolysis and was weaned off dialysis. The aspirated artery thrombus contained tumor cells, proving our diagnosis of acute kidney injury secondary to bilateral renal artery tumor embolism. In cancer patients, endovascular intervention may be a useful diagnostic and therapeutic option in cases of acute kidney injury secondary caused by peripheral thromboembolic complications.

摘要

一位 72 岁男性因左后纵隔肿块引起背痛就诊,肿块已包绕并部分浸润降主动脉。诊断为纵隔未分化肉瘤。诊断后,患者出现突发性无尿。增强 CT 显示双侧肾动脉起始处增强缺损。患者接受了导管定向溶栓治疗,并停止了透析。抽吸的动脉血栓含有肿瘤细胞,证实了我们的诊断,即双侧肾动脉肿瘤栓塞继发的急性肾损伤。在癌症患者中,血管内介入可能是继发于外周血栓栓塞并发症的急性肾损伤的一种有用的诊断和治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33aa/8263193/cc0a449d4751/1349-7235-60-1907-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33aa/8263193/122904853728/1349-7235-60-1907-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33aa/8263193/cc0a449d4751/1349-7235-60-1907-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33aa/8263193/122904853728/1349-7235-60-1907-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33aa/8263193/cc0a449d4751/1349-7235-60-1907-g002.jpg

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本文引用的文献

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Acute kidney injury in the patient with cancer.癌症患者的急性肾损伤
Kidney Res Clin Pract. 2019 Sep 30;38(3):295-308. doi: 10.23876/j.krcp.19.042.
2
Case Series of Pulmonary Tumor Embolism and Intravascular Lymphoma: Evaluation of the Usefulness of Pulmonary Microvascular Cytology.肺肿瘤栓塞和血管内淋巴瘤病例系列:肺微血管细胞学应用价值评估
Intern Med. 2016;55(18):2679-84. doi: 10.2169/internalmedicine.55.6855. Epub 2016 Sep 15.
3
Acute renal artery occlusion: Presentation, treatment, and outcome.急性肾动脉闭塞:临床表现、治疗及预后
J Vasc Surg. 2016 Oct;64(4):1026-32. doi: 10.1016/j.jvs.2016.04.043. Epub 2016 Jun 23.
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Thromboembolism as a cause of renal artery occlusion and acute kidney injury: the recovery of kidney function after two weeks.血栓栓塞作为肾动脉闭塞和急性肾损伤的一个原因:两周后肾功能的恢复
Case Rep Nephrol Urol. 2014 Apr 17;4(1):82-7. doi: 10.1159/000362538. eCollection 2014 Jan.
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Spontaneous showering of tumor emboli in a patient with advanced primary lung cancer: a case report.晚期原发性肺癌患者肿瘤栓子的自发性脱落:一例报告
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Arterial tumor embolism caused by metastatic melanoma: case report and literature review.转移性黑色素瘤引起的动脉肿瘤栓塞:病例报告及文献综述
J Vasc Surg. 2002 Jul;36(1):191-3. doi: 10.1067/mva.2002.123327.
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