Iliadi Konstantin G, Gluscencova Oxana B, Boulianne Gabrielle L
Program in Developmental and Stem Cell Biology, The Hospital For Sick Children , Toronto, ON , Canada.
Program in Developmental and Stem Cell Biology, The Hospital For Sick Children, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Front Psychiatry. 2016 Aug 31;7:153. doi: 10.3389/fpsyt.2016.00153. eCollection 2016.
Psychomotor behaviors are governed by fine relationships between physical activity and cognitive functions. Disturbances in psychomotor development and performance are a hallmark of many mental illnesses and often appear as observable and measurable behaviors. Here, we describe a new method called an "equilibrist test," which can be used to quantify psychomotor learning and performance in Drosophila. We also show how this test can be used to quantify motor disturbances at relatively early stages in the development of neurodegenerative diseases.
精神运动行为受身体活动与认知功能之间精确关系的支配。精神运动发育和表现的紊乱是许多精神疾病的一个标志，并且常常表现为可观察和可测量的行为。在此，我们描述了一种名为“平衡测试”的新方法，该方法可用于量化果蝇的精神运动学习和表现。我们还展示了如何使用该测试来量化神经退行性疾病发展相对早期阶段的运动紊乱。
