Kaufmann Christopher N, Spira Adam P, Depp Colin A, Mojtabai Ramin
Christopher N. Kaufmann and Colin A. Depp are with the Sam and Rose Stein Institute for Research on Aging and the Department of Psychiatry, University of California San Diego School of Medicine, La Jolla, CA. Adam P. Spira and Ramin Mojtabai are with the Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Am J Public Health. 2016 Nov;106(11):2019-2025. doi: 10.2105/AJPH.2016.303382. Epub 2016 Sep 15.
To assess trends in continuing and new prescriptions for sedative-hypnotic medications, including benzodiazepines (BZDs) and non-BZD receptor agonists (nBZRAs).
Data came from the National Ambulatory Medical Care Survey and comprised 287 288 randomly sampled patient visits. Physicians reported medications prescribed and whether they were "continuing" or "new" prescriptions. We assessed trends in continuing BZD, new BZD, continuing nBZRA, and new nBZRA prescriptions from 2005 to 2012.
Proportions of visits with continuing prescriptions increased from 3.4% in 2005 to 4.7% in 2012 (P < .01) for BZDs, and from 1.0% to 1.7% (P < .01) for nBZRAs. We noted no changes in new prescriptions. We observed the same patterns across patient age and physician specialties, except psychiatry. Despite no growth over time, the prevalence of visits involving continuing and new BZD and nBZRA prescriptions was much higher in psychiatry than in primary care and other specialties.
Increased sedative-hypnotic prescribing in recent years may be attributable to long-term growth in continuing prescriptions, rather than new prescriptions. Public Health Implications. Findings call for renewed efforts to limit continuing prescribing of sedative-hypnotics to reduce their use in the population.
评估包括苯二氮䓬类药物(BZD)和非BZD受体激动剂(nBZRA)在内的镇静催眠药物持续处方和新处方的趋势。
数据来自国家门诊医疗护理调查,包括287288次随机抽样的患者就诊。医生报告所开的药物以及这些药物是“持续”处方还是“新”处方。我们评估了2005年至2012年BZD持续处方、BZD新处方、nBZRA持续处方和nBZRA新处方的趋势。
BZD持续处方的就诊比例从2005年的3.4%增至2012年的4.7%(P<0.01),nBZRA持续处方的就诊比例从1.0%增至1.7%(P<0.01)。我们发现新处方没有变化。除精神病学外,我们在患者年龄和医生专业方面观察到相同的模式。尽管随着时间推移没有增长,但涉及BZD和nBZRA持续处方及新处方的就诊患病率在精神病学领域远高于初级保健和其他专业。
近年来镇静催眠药物处方增加可能归因于持续处方的长期增长,而非新处方。对公共卫生的影响。研究结果呼吁重新努力限制镇静催眠药物的持续处方,以减少其在人群中的使用。