巴基斯坦白沙瓦耐多药结核病患者家庭接触者的筛查结果
Screening outcomes of household contacts of multidrug-resistant tuberculosis patients in Peshawar, Pakistan.
作者信息
Javaid Arshad, Khan Mazhar Ali, Khan Mir Azam, Mehreen Sumaira, Basit Anila, Khan Raza Ali, Ihtesham Muhammad, Ullah Irfan, Khan Afsar, Ullah Ubaid
机构信息
Post Graduate Medical Institute, Lady Reading Hospital, Peshawar, Pakistan; Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan.
Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan.
出版信息
Asian Pac J Trop Med. 2016 Sep;9(9):909-912. doi: 10.1016/j.apjtm.2016.07.017. Epub 2016 Jul 26.
OBJECTIVE
To assess the profile of TB/multidrug-resistant TB (MDR-TB) among household contacts of MDR-TB patients.
METHODS
Close contacts of MDR-TB patients were traced in the cross-sectional study. Different clinical, radiological and bacteriological were performed to rule out the evidence of TB/MDR-TB.
RESULTS
Between January 2012 and December 2012, a total of 200 index MDR-TB patients were initiated on MDR-TB treatment, out of which home visit and contacts screening were conducted for 154 index cases. Of 610 contacts who could be studied, 41 (17.4%) were diagnosed with MDR-TB and 10 (4.2%) had TB. The most common symptoms observed were cough, chest pain and fever.
CONCLUSIONS
The high incidence of MDR-TB among close contacts emphasize the need for effective contact screening programme of index MDR-TB cases in order to cut the chain of transmission of this disease.
目的
评估耐多药结核病（MDR-TB）患者家庭接触者中结核病/MDR-TB的情况。
方法
在横断面研究中追踪MDR-TB患者的密切接触者。进行了不同的临床、放射学和细菌学检查以排除结核病/MDR-TB的证据。
结果
2012年1月至2012年12月期间，共有200例耐多药结核病患者开始接受耐多药结核病治疗，其中对154例患者进行了家访和接触者筛查。在610名可研究的接触者中，41例（17.4%）被诊断为耐多药结核病，10例（4.2%）患有结核病。观察到的最常见症状是咳嗽、胸痛和发热。
结论
密切接触者中耐多药结核病的高发病率强调了对耐多药结核病索引病例进行有效接触者筛查计划的必要性，以切断这种疾病的传播链。
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