Guo Jun-Cheng, Tian Zhi-Liang, Wang Xiao-Dan, Guo Min, Li Meng-Yong-Wei, Gao Yun-Suo, Jiang Xiang-Ling, Fu Lin-Mei, Huang Tao, Li Xiang, Yu Shu-Feng, You Li
People's Hospital of Hainan Province, Haikou, Hainan, 570311, China; Affiliated Hainan Hospital, University of South China, Haikou, Hainan, 570311, China.
The Second Hospital, University of South China, Hengyang, Hunan, China.
Asian Pac J Trop Med. 2016 Sep;9(9):913-915. doi: 10.1016/j.apjtm.2016.07.011. Epub 2016 Jul 26.
To investigate residents' psychological stress factors and research the correlation between post-traumatic stress disorder (PTSD) and platelet 5-HT concentrations so as to provide scientific bases for diagnosis and treatment of PTSD and psychological intervention for people in the disaster area.
A questionnaire survey of 5500 residents who have accepted psychological help was conducted by the emphatic investigation method. While high performance liquid chromatography was used to detect the platelet serotonin concentration of 100 PTSD patients and 100 healthy people.
(1) Of the 5114 cases, 3167 (61.93%) showed positive results in screening for psychological stress symptoms, and 399 (7.8%) were tested having apparent PTSD symptoms. Male and female prevalence showed no significant difference (χ(2) = -0.380, P = 0.704). The differences of prevalence between different age groups were statistically significant (χ(2) = 381.89, P = 0.000). (2) The differences in the level of platelet 5-HT between PTSD patients and normal control group were statistically significant.
The typhoon of Hainan Province caused relatively large psychological problems to the disaster victims. Compared with normal control group, the platelet 5-HT levels of PTSD patients in the disaster areas are lower. It may be related to incidents exposure levels, cultural background, religious ideas, social concerns and psychological rescue of the residents who live in the disaster areas of Hainan.
探讨居民心理应激因素，研究创伤后应激障碍（PTSD）与血小板5-羟色胺（5-HT）浓度之间的相关性，为PTSD的诊断治疗及对灾区人群进行心理干预提供科学依据。
采用重点调查法对5500名接受心理援助的居民进行问卷调查。同时采用高效液相色谱法检测100例PTSD患者和100名健康人的血小板5-羟色胺浓度。
（1）5114例中，心理应激症状筛查阳性3167例（61.93%），确诊有明显PTSD症状399例（7.8%）。男女患病率差异无统计学意义（χ(2)= -0.380，P = 0.704）。不同年龄组患病率差异有统计学意义（χ(2)= 381.89，P = 0.000）。（2）PTSD患者与正常对照组血小板5-HT水平差异有统计学意义。
海南省台风给受灾群众造成了较大心理问题。与正常对照组相比，灾区PTSD患者血小板5-HT水平较低。这可能与海南灾区居民的事件暴露程度、文化背景、宗教观念、社会关注及心理救援等有关。
