Wenderoth U K, Bachor R, Egghart G, Frohneberg D, Miller K, Hautmann R
Urologische Universitätsklinik Ulm.
Urologe A. 1989 Jul;28(4):204-8.
Between April 1986 and April 1989, each of 108 patients received an ileum neobladder, 94 patients for total bladder substitution after radical cysto-prostatectomy and 14 for augmentation of a fibrotic and contracted bladder following tuberculosis, interstitial cystitis or radiotherapy of the pelvis. The operative technique is standardized, relatively simple and safe, and it prevents upper urinary tract deterioration and reflux. Continence is preserved in more than 80% of all patients by the function of the external urethral sphincter and by the high capacity and the low internal pressure of the intestinal reservoir. Follow-up of more than 3 months postoperatively was possible in 96 patients, the evaluation including micturition behavior at home and a urodynamic investigation. Stress incontinence requiring correction by an artificial sphincter was found in 3 and nocturnal incontinence necessitating some external device in 6 patients. There was no perioperative mortality. Local tumor recurrence and/or metastases occurred in 14 patients; 7 patients died postoperatively, 5 owing to tumor progression, 1 of pneumonia and serve metabolic acidosis, and 1 owing to septicemia of unknown cause. Re-operation was necessary in 13 patients, in 6 because of mechanical ileus or intra-abdominal abscess, in 3 because of stenosis of the uretero-ileal anastomosis, in 1 because of tumor progression, in 1 because of vesico-vaginal fistula, in 1 patient because of incisional hernia, and in 1 because of wound dehiscence. Urethrotomy or dilatation of urethral strictures was necessary in 8 patients. All other early and late complications were rare and could be managed by conservative means.(ABSTRACT TRUNCATED AT 250 WORDS)
1986年4月至1989年4月期间,108例患者接受了回肠新膀胱术,其中94例因根治性膀胱前列腺切除术后行全膀胱替代,14例因结核、间质性膀胱炎或盆腔放疗后膀胱纤维化和挛缩而行膀胱扩大术。手术技术标准化,相对简单且安全,可防止上尿路恶化和反流。由于外尿道括约肌的功能以及肠道贮尿囊的大容量和低内压,超过80%的患者保持了控尿能力。96例患者术后随访超过3个月,评估包括在家排尿行为和尿动力学检查。3例患者出现压力性尿失禁需要人工括约肌矫正,6例患者出现夜间尿失禁需要一些外部装置。无围手术期死亡。14例患者发生局部肿瘤复发和/或转移;7例患者术后死亡,5例因肿瘤进展,1例因肺炎和严重代谢性酸中毒,1例因不明原因的败血症。13例患者需要再次手术,6例因机械性肠梗阻或腹腔内脓肿,3例因输尿管回肠吻合口狭窄,1例因肿瘤进展,1例因膀胱阴道瘘,1例因切口疝,1例因伤口裂开。8例患者需要行尿道切开术或尿道狭窄扩张术。所有其他早期和晚期并发症均少见,可通过保守方法处理。(摘要截断于250字)