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[犬脑内接种狂犬病街毒后的顿挫型和复发型狂犬病]

[Abortive and recurrent rabies in dogs intracerebrally infected with the rabies street virus].

作者信息

Gribencha S V, Gribanova L Ia, Mal'kov G B, Barinskiĭ I F

出版信息

Vopr Virusol. 1989 Mar-Apr;34(2):217-21.

PMID:2763514
Abstract

In the experiments on dogs inoculated intracerebrally with the "paralytic rabies" variant of the "Yak" strain of street rabies virus we observed spontaneous recovery of 1 out of 5 sick animals. Rabies in this dog was verified by three isolations of the virus from the saliva during the disease and by an increase of antibody titres in the time course of to 6776. In another experiment, among 7 dogs developing rabies after intracerebral inoculation with the "convulsive rabies" variant of the virus one animal showed recurrent form of rabies. The diagnosis of rabies was confirmed by isolation of the virus from the saliva in primary disease as well as by virus isolation from the salivary glands and the brain of the dog dying with recurrent rabies.

摘要

在对用街狂犬病毒“亚克”株的“麻痹型狂犬病”变种进行脑内接种的犬类实验中,我们观察到5只患病动物中有1只自发康复。通过在病程中从唾液中三次分离出病毒以及抗体滴度在病程中升至6776,证实了这只犬感染了狂犬病。在另一项实验中,7只经脑内接种该病毒“惊厥型狂犬病”变种后患上狂犬病的犬类中,有1只出现了狂犬病复发形式。通过在初次发病时从唾液中分离出病毒以及从死于狂犬病复发的犬的唾液腺和大脑中分离出病毒,证实了狂犬病的诊断。

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