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[狂犬病街毒株变种的生物学特性]

[Biological properties of variants of the rabies street virus].

作者信息

Gribanova L Ia, Gribencha S V, Mal'kov G B, Barinskiĭ I F

出版信息

Vopr Virusol. 1988 Mar-Apr;33(2):201-6.

PMID:3414067
Abstract

Experiments in dogs inoculated intracerebrally with biological variants of paralytic (PRV) and convulsive (CRV) rabies virus isolated from the Yak strain population of street rabies virus demonstrated distinct differences in the biological properties of the variants PRV induced in dogs paralytic rabies with a short incubation period (average 6.4 days) and CRV induced an atypical convulsive form characterized by attacks of tonic convulsions of the body, legs, and head twitching, and a longer incubation period (18.5 and 9.6 days, respectively). This explains a wide variability of the biological properties of street rabies virus strains.

摘要

用从街狂犬病毒雅库毒株群体中分离出的麻痹型(PRV)和惊厥型(CRV)狂犬病毒的生物学变种对犬进行脑内接种实验,结果表明,PRV变种在犬中诱发潜伏期短(平均6.4天)的麻痹性狂犬病,而CRV诱发以身体、腿部强直性惊厥发作和头部抽搐为特征的非典型惊厥形式,且潜伏期更长(分别为18.5天和9.6天)。这解释了街狂犬病毒株生物学特性的广泛变异性。

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