Chen John J, Kardon Randy H
Department of Ophthalmology (JJC), Mayo Clinic, Rochester, Minnesota; Department of Ophthalmology and Visual Sciences (JJC, RHK), University of Iowa, Iowa City, Iowa; and Department of Veterans Affairs (RHK), Center for the Prevention and Treatment of Visual Loss, Iowa City, Iowa.
J Neuroophthalmol. 2016 Dec;36(4):417-438. doi: 10.1097/WNO.0000000000000422.
Optical coherence tomography (OCT) has become an important tool for diagnosing optic nerve disease. The structural details and reproducibility of OCT continues to improve with further advances in technology. However, artifacts and misinterpretation of OCT can lead to clinical misdiagnosis of diseases if they go unrecognized.
A literature review using PubMed combined with clinical and research experience.
We describe the most common artifacts and errors in interpretation seen on OCT in both optic nerve and ganglion cell analyses. We provide examples of the artifacts, discuss the causes, and provide methods of detecting them. In addition, we discuss a systematic approach to OCT analysis to facilitate the recognition of artifacts and to avoid clinical misinterpretation.
While OCT is invaluable in diagnosing optic nerve disease, we need to be cognizant of the artifacts that can occur with OCT. Failure to recognize some of these artifacts can lead to misdiagnoses and inappropriate investigations.
光学相干断层扫描（OCT）已成为诊断视神经疾病的重要工具。随着技术的进一步发展，OCT的结构细节和可重复性不断提高。然而，如果不被识别，OCT的伪像和错误解读可能导致疾病的临床误诊。
使用PubMed进行文献综述，并结合临床和研究经验。
我们描述了在视神经和神经节细胞分析中OCT上最常见的伪像和解读错误。我们提供了伪像的示例，讨论了其原因，并提供了检测它们的方法。此外，我们讨论了一种OCT分析的系统方法，以促进伪像的识别并避免临床错误解读。
虽然OCT在诊断视神经疾病方面具有重要价值，但我们需要认识到OCT可能出现的伪像。未能识别其中一些伪像可能导致误诊和不适当的检查。
